Novel malyngamide structural analogs: synthesis and biological evaluation
G. Venkateswar Reddy
1
,
T. Vijaya Kumar
1
,
B Siva
1
,
K Suresh Babu
1
,
P.V Srinivas
1, 2
,
Irum Sehar
3
,
A. K. Saxena
3
,
J.Madhusudana Rao
1
1
2
Process, Research and Development Center, Biocon Limited, Bangalore, India
|
Publication type: Journal Article
Publication date: 2013-01-13
scimago Q2
wos Q3
SJR: 0.470
CiteScore: 5.1
Impact factor: 3.1
ISSN: 10542523, 15548120
Organic Chemistry
General Pharmacology, Toxicology and Pharmaceutics
Abstract
In the course of our search for new anticancer agents, a series of novel malyngamide derivatives were synthesized by sharpless asymmetric epoxidation, followed by Julia-Kocinski olefination reactions as key reaction sequence. Anticancer activities of all these derivatives were screened against IMR-32, SF-295, SKNSH, HeLa, Colon-502713, SW-620, and Hop-62 cell lines for the first time.
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Total citations:
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Citations from 2024:
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GOST
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Reddy G. V. et al. Novel malyngamide structural analogs: synthesis and biological evaluation // Medicinal Chemistry Research. 2013. Vol. 22. No. 10. pp. 4581-4591.
GOST all authors (up to 50)
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Reddy G. V., Kumar T. V., Siva B., Babu K. S., Srinivas P., Sehar I., Saxena A. K., Rao J. Novel malyngamide structural analogs: synthesis and biological evaluation // Medicinal Chemistry Research. 2013. Vol. 22. No. 10. pp. 4581-4591.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s00044-013-0466-y
UR - https://doi.org/10.1007/s00044-013-0466-y
TI - Novel malyngamide structural analogs: synthesis and biological evaluation
T2 - Medicinal Chemistry Research
AU - Reddy, G. Venkateswar
AU - Kumar, T. Vijaya
AU - Siva, B
AU - Babu, K Suresh
AU - Srinivas, P.V
AU - Sehar, Irum
AU - Saxena, A. K.
AU - Rao, J.Madhusudana
PY - 2013
DA - 2013/01/13
PB - Springer Nature
SP - 4581-4591
IS - 10
VL - 22
SN - 1054-2523
SN - 1554-8120
ER -
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BibTex (up to 50 authors)
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@article{2013_Reddy,
author = {G. Venkateswar Reddy and T. Vijaya Kumar and B Siva and K Suresh Babu and P.V Srinivas and Irum Sehar and A. K. Saxena and J.Madhusudana Rao},
title = {Novel malyngamide structural analogs: synthesis and biological evaluation},
journal = {Medicinal Chemistry Research},
year = {2013},
volume = {22},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s00044-013-0466-y},
number = {10},
pages = {4581--4591},
doi = {10.1007/s00044-013-0466-y}
}
Cite this
MLA
Copy
Reddy, G. Venkateswar, et al. “Novel malyngamide structural analogs: synthesis and biological evaluation.” Medicinal Chemistry Research, vol. 22, no. 10, Jan. 2013, pp. 4581-4591. https://doi.org/10.1007/s00044-013-0466-y.