Bulletin of Experimental Biology and Medicine, volume 147, issue 6, pages 715-718

The Rat Spermatogenesis after Injection of Paclitaxel (Antitumor Agent)

T G Borovskaya ^{1, 2}

V E Goldberg ^{1, 2}

O A Rumpel ^{1, 2}

A V Pahomova ^{1, 2}

A V Perova ^{1, 2}

E D Goldberg ^{1, 2}

Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |

Institute of Oncology, Tomsk Research Cente, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |

Publication type: Journal Article

Publication date: 2009-06-01

Springer Nature

Journal: Bulletin of Experimental Biology and Medicine

scimago Q3

wos Q4

SJR: 0.245

CiteScore: 1.5

Impact factor: 0.9

ISSN: 00074888, 15738221, 03659615, 24131008

DOI: 10.1007/s10517-009-0596-x

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General Biochemistry, Genetics and Molecular Biology

General Medicine

Abstract

Morphological and functional characteristics of spermatogenesis in rats were studied during the early and delayed periods after single injection of paclitaxel (antitumor agent) in the maximum tolerated dose. The drug induced structural changes in the gonads associated with oligospermia and increased number of pathological forms of spermatozoa with reduced functional activity.

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Bulletin of Experimental Biology and Medicine	Bulletin of Experimental Biology and Medicine, 3, 30% Bulletin of Experimental Biology and Medicine 3 publications, 30%
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Journal of Biochemical and Molecular Toxicology	Journal of Biochemical and Molecular Toxicology, 1, 10% Journal of Biochemical and Molecular Toxicology 1 publication, 10%
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Wiley	Wiley, 4, 40% Wiley 4 publications, 40%
Springer Nature	Springer Nature, 3, 30% Springer Nature 3 publications, 30%
Elsevier	Elsevier, 2, 20% Elsevier 2 publications, 20%
Taylor & Francis	Taylor & Francis, 1, 10% Taylor & Francis 1 publication, 10%
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Publisher

Springer Nature

Journal

Bulletin of Experimental Biology and Medicine

scimago Q3

wos Q4

SJR

0.245

CiteScore

1.5

Impact factor

0.9

ISSN

00074888 (Print)

15738221 (Electronic)

03659615 (Print)

24131008 (Electronic)

Profiles

Borovskaya, Tatyyana Gennadyevna

The Rat Spermatogenesis after Injection of Paclitaxel (Antitumor Agent)

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