volume 159 issue 6 pages 743-746

Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure

A M Dygai 1
A V Chaikovskii 1
V. V. Zhdanov 1
G N Zyuzkov 1
L A Stavrova 1
V. V. UDUT 1
L A Miroshnichenko 1
E V Simanina 1
M E Poluektova 1
Publication typeJournal Article
Publication date2015-10-29
scimago Q3
wos Q4
SJR0.277
CiteScore1.5
Impact factor0.6
ISSN00074888, 15738221, 03659615, 24131008
General Biochemistry, Genetics and Molecular Biology
General Medicine
Abstract
A decrease in the total number of sperm cells and reduction of spermatogonium population were observed upon cytostatic damage of spermatogenous tissue caused by single paclitaxel administration. It was established that the paclitaxel-induced damage to the testicular tissue is underlain by reduction of its regenerative potential consisting in depletion of regional precursor pool. Changes in functional activity of progenitor cells were caused not only by direct action of paclitaxel, but also by suppression of the secretory function of the tissue microenvironment.
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GOST Copy
Dygai A. M. et al. Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure // Bulletin of Experimental Biology and Medicine. 2015. Vol. 159. No. 6. pp. 743-746.
GOST all authors (up to 50) Copy
Dygai A. M., Chaikovskii A. V., Zhdanov V. V., Zyuzkov G. N., Stavrova L. A., UDUT V. V., Miroshnichenko L. A., Simanina E. V., Borovskaya T. G., Poluektova M. E. Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure // Bulletin of Experimental Biology and Medicine. 2015. Vol. 159. No. 6. pp. 743-746.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s10517-015-3064-9
UR - https://doi.org/10.1007/s10517-015-3064-9
TI - Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure
T2 - Bulletin of Experimental Biology and Medicine
AU - Dygai, A M
AU - Chaikovskii, A V
AU - Zhdanov, V. V.
AU - Zyuzkov, G N
AU - Stavrova, L A
AU - UDUT, V. V.
AU - Miroshnichenko, L A
AU - Simanina, E V
AU - Borovskaya, T G
AU - Poluektova, M E
PY - 2015
DA - 2015/10/29
PB - Springer Nature
SP - 743-746
IS - 6
VL - 159
PMID - 26515175
SN - 0007-4888
SN - 1573-8221
SN - 0365-9615
SN - 2413-1008
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Dygai,
author = {A M Dygai and A V Chaikovskii and V. V. Zhdanov and G N Zyuzkov and L A Stavrova and V. V. UDUT and L A Miroshnichenko and E V Simanina and T G Borovskaya and M E Poluektova},
title = {Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure},
journal = {Bulletin of Experimental Biology and Medicine},
year = {2015},
volume = {159},
publisher = {Springer Nature},
month = {oct},
url = {https://doi.org/10.1007/s10517-015-3064-9},
number = {6},
pages = {743--746},
doi = {10.1007/s10517-015-3064-9}
}
MLA
Cite this
MLA Copy
Dygai, A. M., et al. “Responses of Spermatogenous Tissue and Mechanisms of Their Development Upon Cytostatic Exposure.” Bulletin of Experimental Biology and Medicine, vol. 159, no. 6, Oct. 2015, pp. 743-746. https://doi.org/10.1007/s10517-015-3064-9.