Bulletin of Experimental Biology and Medicine, volume 166, issue 1, pages 7-10
Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia
T G Borovskaya
1
,
S I Kamalova
1
,
N. A. Krivova
2
,
O B Zaeva
2
,
M E Poluektova
1
,
A V Vychuzhanina
1
,
V A Grigoreva
1
,
M B Plotnikov
1
,
V E Goldberg
3
Publication type: Journal Article
Publication date: 2018-11-18
scimago Q3
wos Q4
SJR: 0.245
CiteScore: 1.5
Impact factor: 0.9
ISSN: 00074888, 15738221, 03659615, 24131008
General Biochemistry, Genetics and Molecular Biology
General Medicine
Abstract
The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology, functions, and redox processes in the reproductive cells of male rats was studied on the model of experimental pathospermia. All antioxidants reduced the percentage of degenerative forms of spermatozoa. Dibornol was most effective. Dihydroquercetin and p-tyrosol did not increase the total number of spermatozoa and the percentage of their mobile forms. These indicators were improved only by dibornol. After administration of all test drugs, the antioxidant potential of spermatozoa increased and did not significantly differ from the baseline values.
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