Bulletin of Experimental Biology and Medicine, volume 166, issue 2, pages 217-221
Protective Effect of Polysaccharides from Tussilago farfara L. on Bone Marrow Cells and Small Intestinal Epithelium Under Conditions of Polychemotherapy Evaluated by DNA Comet Assay
E A Safonova
1
,
K A Lopatina
1
,
A V Vychuzhanina
1
,
V A Mashanova
1
,
T G Razina
1
,
T G Borovskaya
1
,
E P Zueva
1
,
A. M. Gur’ev
2
,
M. V. Belousov
2
Publication type: Journal Article
Publication date: 2018-11-28
scimago Q3
wos Q4
SJR: 0.245
CiteScore: 1.5
Impact factor: 0.9
ISSN: 00074888, 15738221, 03659615, 24131008
General Biochemistry, Genetics and Molecular Biology
General Medicine
Abstract
Using DNA comet assay we found that polysaccharides from Tussilago farfara L. reduced the intensity of polychemotherapy-induced apoptosis and DNA damage in bone marrow cells and small intestinal epithelium of C57Bl/6 mice, which attested to genoprotective properties of these polysaccharides.
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