A nature-inspired concise synthesis of (+)-ent-chromazonarol
2
National Institute of Biological Sciences (NIBS), Beijing, China
|
Publication type: Journal Article
Publication date: 2013-01-07
scimago Q1
wos Q1
SJR: 2.377
CiteScore: 13.8
Impact factor: 9.7
ISSN: 16747291, 18691870
General Chemistry
Abstract
A large number of sesquiterpene quinone/hydroquinone natural products including (+)-ent-chromazonarol have been isolated and received great attention from the synthetic community. Herein, we report a nature-inspired concise synthesis of (+)-ent-chromazonarol in 4 steps from a readily available starting material. The synthesis relied on a Lewis acid mediated cyclization which correctly installed two vicinal stereocenters in one step. This highly efficient synthetic route allows us to further prepare natural product congeners for further biological studies.
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Metrics
13
Total citations:
13
Citations from 2024:
4
(30.77%)
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GOST
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Huang J., Lei X. A nature-inspired concise synthesis of (+)-ent-chromazonarol // Science China Chemistry. 2013. Vol. 56. No. 3. pp. 349-353.
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Huang J., Lei X. A nature-inspired concise synthesis of (+)-ent-chromazonarol // Science China Chemistry. 2013. Vol. 56. No. 3. pp. 349-353.
Cite this
RIS
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TY - JOUR
DO - 10.1007/s11426-012-4826-0
UR - https://doi.org/10.1007/s11426-012-4826-0
TI - A nature-inspired concise synthesis of (+)-ent-chromazonarol
T2 - Science China Chemistry
AU - Huang, Jiehui
AU - Lei, Xiaoguang
PY - 2013
DA - 2013/01/07
PB - Springer Nature
SP - 349-353
IS - 3
VL - 56
SN - 1674-7291
SN - 1869-1870
ER -
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BibTex (up to 50 authors)
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@article{2013_Huang,
author = {Jiehui Huang and Xiaoguang Lei},
title = {A nature-inspired concise synthesis of (+)-ent-chromazonarol},
journal = {Science China Chemistry},
year = {2013},
volume = {56},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s11426-012-4826-0},
number = {3},
pages = {349--353},
doi = {10.1007/s11426-012-4826-0}
}
Cite this
MLA
Copy
Huang, Jiehui, et al. “A nature-inspired concise synthesis of (+)-ent-chromazonarol.” Science China Chemistry, vol. 56, no. 3, Jan. 2013, pp. 349-353. https://doi.org/10.1007/s11426-012-4826-0.