Solid Phase Organometallic Chemistry

This review covers recent results in the area of solid phase organometallic chemistry during the period 2000–2006. The focus is on carbon–carbon bond formation, but other aspects of organometallic reactions are also discussed. This includes the use of metal complexes as linkers, synthesis of biologically active compounds and complex natural product analogues, development of diversifying cleavage strategies, and testing the stability of new linkers and polymers under different reaction conditions. In many cases a direct comparison has been made between solid phase and solution phase chemistry. Thus, the advantages of performing reactions on polymer-supported substrates in terms of avoiding side reactions and facilitating product/metal separation are highlighted.