BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea
O F Smetanina
1
,
A N Yurchenko
2
,
A I Kalinovskii
1
,
D V Berdyshev
1
,
A V Gerasimenko
3
,
M V Pivkin
1
,
N N Slinkina
1
,
P S Dmitrenok
1
,
N I Menzorova
1
,
Sh Sh Afiyatullov
1
Publication type: Journal Article
Publication date: 2011-07-29
scimago Q3
wos Q4
SJR: 0.296
CiteScore: 1.3
Impact factor: 0.9
ISSN: 00093130, 15738388
General Chemistry
General Biochemistry, Genetics and Molecular Biology
Plant Science
Abstract
The new compound isoacremine D (1) and acremine A (2) that was previously unknown for marine organisms were isolated from the marine isolate of the fungus Myceliophthora lutea. It was found that acremine A in CHCl3 was converted through the action of light into spirocompounds called by us spiroacremines A (3) and B (4). The structures of the compounds were elucidated based on NMR spectroscopic and high-resolution mass spectrometric data. The absolute stereochemistry of the spiroacremines was determined by Mosher’s method. It was shown that isoacremine D exhibited antimicrobial activity against Staphylococcus aureus at a concentration of 200 μg/mL and cytotoxic activity against embryos of the sea urchin Strongylocentrotus nudus. It was found that 1–4 exhibited cytotoxic activity against sea urchin sperm cells.
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Smetanina O. F. et al. BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea // Chemistry of Natural Compounds. 2011. Vol. 47. No. 3. pp. 385-390.
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Smetanina O. F., Yurchenko A. N., Kalinovskii A. I., Berdyshev D. V., Gerasimenko A. V., Pivkin M. V., Slinkina N. N., Dmitrenok P. S., Menzorova N. I., Afiyatullov S. S. BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea // Chemistry of Natural Compounds. 2011. Vol. 47. No. 3. pp. 385-390.
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TY - JOUR
DO - 10.1007/S10600-011-9940-2
UR - https://doi.org/10.1007/S10600-011-9940-2
TI - BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea
T2 - Chemistry of Natural Compounds
AU - Smetanina, O F
AU - Yurchenko, A N
AU - Kalinovskii, A I
AU - Berdyshev, D V
AU - Gerasimenko, A V
AU - Pivkin, M V
AU - Slinkina, N N
AU - Dmitrenok, P S
AU - Menzorova, N I
AU - Afiyatullov, Sh Sh
PY - 2011
DA - 2011/07/29
PB - Springer Nature
SP - 385-390
IS - 3
VL - 47
SN - 0009-3130
SN - 1573-8388
ER -
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BibTex (up to 50 authors)
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@article{2011_Smetanina,
author = {O F Smetanina and A N Yurchenko and A I Kalinovskii and D V Berdyshev and A V Gerasimenko and M V Pivkin and N N Slinkina and P S Dmitrenok and N I Menzorova and Sh Sh Afiyatullov},
title = {BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea},
journal = {Chemistry of Natural Compounds},
year = {2011},
volume = {47},
publisher = {Springer Nature},
month = {jul},
url = {https://doi.org/10.1007/S10600-011-9940-2},
number = {3},
pages = {385--390},
doi = {10.1007/S10600-011-9940-2}
}
Cite this
MLA
Copy
Smetanina, O. F., et al. “BIOLOGICALLY ACTIVE METABOLITES FROM THE MARINE ISOLATE OF THE FUNGUS Myceliophthora lutea.” Chemistry of Natural Compounds, vol. 47, no. 3, Jul. 2011, pp. 385-390. https://doi.org/10.1007/S10600-011-9940-2.
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