Gender differences in pulmonary and immune response in acute experimental endotoxicosis
Publication type: Journal Article
Publication date: 2012-07-01
scimago Q3
wos Q4
SJR: 0.277
CiteScore: 1.5
Impact factor: 0.6
ISSN: 00074888, 15738221, 03659615, 24131008
PubMed ID:
22866306
General Biochemistry, Genetics and Molecular Biology
General Medicine
Abstract
Differences in the immune and inflammatory response were revealed in the lungs of male and female Wistar rats on day 1 after administration of LPS in a dose inducing the development of acute bacterial endotoxemia. Females showed more pronounced morphofunctional signs of immune system activation than males: this was characterized by more severe accidental involution of the thymus, devastation of the splenic white pulp, and enhanced production of IL-4, IL-12, and TNF-α by splenocytes. In males, production of the above cytokines decreased and inflammation in the lungs was more pronounced at these terms.
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Total citations:
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Citations from 2025:
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(12.5%)
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GOST
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Kosyreva A. M., Simonova E. Yu., Makarova O. V. Gender differences in pulmonary and immune response in acute experimental endotoxicosis // Bulletin of Experimental Biology and Medicine. 2012. Vol. 153. No. 3. pp. 340-342.
GOST all authors (up to 50)
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Kosyreva A. M., Simonova E. Yu., Makarova O. V. Gender differences in pulmonary and immune response in acute experimental endotoxicosis // Bulletin of Experimental Biology and Medicine. 2012. Vol. 153. No. 3. pp. 340-342.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s10517-012-1710-z
UR - https://doi.org/10.1007/s10517-012-1710-z
TI - Gender differences in pulmonary and immune response in acute experimental endotoxicosis
T2 - Bulletin of Experimental Biology and Medicine
AU - Kosyreva, A M
AU - Simonova, E Yu
AU - Makarova, O. V.
PY - 2012
DA - 2012/07/01
PB - Springer Nature
SP - 340-342
IS - 3
VL - 153
PMID - 22866306
SN - 0007-4888
SN - 1573-8221
SN - 0365-9615
SN - 2413-1008
ER -
Cite this
BibTex (up to 50 authors)
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@article{2012_Kosyreva,
author = {A M Kosyreva and E Yu Simonova and O. V. Makarova},
title = {Gender differences in pulmonary and immune response in acute experimental endotoxicosis},
journal = {Bulletin of Experimental Biology and Medicine},
year = {2012},
volume = {153},
publisher = {Springer Nature},
month = {jul},
url = {https://doi.org/10.1007/s10517-012-1710-z},
number = {3},
pages = {340--342},
doi = {10.1007/s10517-012-1710-z}
}
Cite this
MLA
Copy
Kosyreva, A. M., et al. “Gender differences in pulmonary and immune response in acute experimental endotoxicosis.” Bulletin of Experimental Biology and Medicine, vol. 153, no. 3, Jul. 2012, pp. 340-342. https://doi.org/10.1007/s10517-012-1710-z.
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