Springer Nature
Chemistry of Heterocyclic Compounds
,  volume 56 ,  issue 6 ,  pages 756-762

Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones

Aleksey V Bukreev 1
, 
Taisia I Akimova 1
, 
Ilya А Osterman 2, 3
, 
Anna N Shakhtina 3
, 
Yuliya V Khudyakova 4
, 
Andrey V Gerasimenko 5
, 
Petr V. Sergiev 2, 3
, 
Olga А Dontsova 2, 3, 6
, 
Pavel I Deryabin 1
, 
Vera B Kolycheva 1
1
 
2
 
3
 
4
 
5
 
6
 
Publication type: Journal Article
Publication date: 2020-06-01
Springer Nature
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
New derivatives of 3,5-dibenzoylspiropiperidinium salts were obtained by the previously developed method of cyclization of Mannich methylidene monobases of arylaliphatic 1,5-diketones and their antibacterial activity was studied. The structure of one of the salts was determined by X-ray structural analysis. The study of the mechanism of action using the pDualrep2 reporter system showed that some compounds cause the SOS response in the bacterial cell.
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Bukreev A. V. et al. Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones // Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 6. pp. 756-762.
GOST all authors (up to 50) Copy
Bukreev A. V., Akimova T. I., Osterman I. А., Shakhtina A. N., Khudyakova Y. V., Gerasimenko A. V., Sergiev P. V., Dontsova O. А., Deryabin P. I., Kolycheva V. B. Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones // Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 6. pp. 756-762.
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TY - JOUR
DO - 10.1007/s10593-020-02727-z
UR - http://link.springer.com/10.1007/s10593-020-02727-z
TI - Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones
T2 - Chemistry of Heterocyclic Compounds
AU - Bukreev, Aleksey V
AU - Akimova, Taisia I
AU - Osterman, Ilya А
AU - Shakhtina, Anna N
AU - Khudyakova, Yuliya V
AU - Gerasimenko, Andrey V
AU - Sergiev, Petr V.
AU - Dontsova, Olga А
AU - Deryabin, Pavel I
AU - Kolycheva, Vera B
PY - 2020
DA - 2020/06/01
PB - Springer Nature
SP - 756-762
IS - 6
VL - 56
SN - 0009-3122
SN - 1573-8353
ER -
BibTex |
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@article{2020_Bukreev,
author = {Aleksey V Bukreev and Taisia I Akimova and Ilya А Osterman and Anna N Shakhtina and Yuliya V Khudyakova and Andrey V Gerasimenko and Petr V. Sergiev and Olga А Dontsova and Pavel I Deryabin and Vera B Kolycheva},
title = {Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones},
journal = {Chemistry of Heterocyclic Compounds},
year = {2020},
volume = {56},
publisher = {Springer Nature},
month = {jun},
url = {http://link.springer.com/10.1007/s10593-020-02727-z},
number = {6},
pages = {756--762},
doi = {10.1007/s10593-020-02727-z}
}
MLA
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Bukreev, Aleksey V., et al. “Structure and antibacterial activity (mediated by the SOS response) of spiropiperidinium salts obtained by cyclization of Mannich bases of arylaliphatic 1,5-diketones.” Chemistry of Heterocyclic Compounds, vol. 56, no. 6, Jun. 2020, pp. 756-762. http://link.springer.com/10.1007/s10593-020-02727-z.