Chemistry of Heterocyclic Compounds

, volume 56 , issue 6 , pages 800-804

Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity

Elena V. Salimova ¹

Aygul A Magafurova ²

Elena V. Tretyakova ¹

Olga S. Kukovinets ²

Lyudmila V. Parfenova ¹

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Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, Russia

Institute of Petrochemistry and Catalysis of the Ufa Federal Research Center of the Russian Academy of Sciences

Ufa Federal Research Center of the Russian Academy of Sciences

Bashkir State University, Ufa, Russia |

Publication type: Journal Article

Publication date: 2020-06-01

Springer Nature

Chemistry of Heterocyclic Compounds

scimago Q4

wos Q4

SJR: 0.243

CiteScore: 2.7

Impact factor: 1.0

ISSN: 00093122, 15738353

DOI: 10.1007/s10593-020-02733-1

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Organic Chemistry

Abstract

New indole derivatives of fusidic acid were synthesized by using the Fischer reaction. The obtained compounds were screened in vitro for antibacterial activity and were found to inhibit the growth of Staphylococcus aureus (MRSA, strain ATCC 43300) at concentrations comparable to fusidic acid. The obtained indole derivatives of fusidic acid were also characterized by relatively low cytotoxicity and minimal hemolytic effect at the highest concentration that was tested (32 μg/ml).

Found

6 citations

Parfenova Lyudmila

🥼 🤝

DSc in Chemistry, associate professor

110 publications, 1 039 citations, 8 reviews

h-index: 17

Institute of Petrochemistry and Catalysis of the Ufa Federal Research Center of the Russian Academy of Sciences

Research interests

Asymmetric metal complex catalysis

Regenerative materials

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Salimova E. V. et al. Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity // Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 6. pp. 800-804.

GOST all authors (up to 50) Copy

Salimova E. V., Magafurova A. A., Tretyakova E. V., Kukovinets O. S., Parfenova L. V. Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity // Chemistry of Heterocyclic Compounds. 2020. Vol. 56. No. 6. pp. 800-804.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1007/s10593-020-02733-1

UR - https://doi.org/10.1007/s10593-020-02733-1

TI - Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity

T2 - Chemistry of Heterocyclic Compounds

AU - Salimova, Elena V.

AU - Magafurova, Aygul A

AU - Tretyakova, Elena V.

AU - Kukovinets, Olga S.

AU - Parfenova, Lyudmila V.

PY - 2020

DA - 2020/06/01

PB - Springer Nature

SP - 800-804

IS - 6

VL - 56

SN - 0009-3122

SN - 1573-8353

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2020_Salimova,

author = {Elena V. Salimova and Aygul A Magafurova and Elena V. Tretyakova and Olga S. Kukovinets and Lyudmila V. Parfenova},

title = {Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity},

journal = {Chemistry of Heterocyclic Compounds},

year = {2020},

volume = {56},

publisher = {Springer Nature},

month = {jun},

url = {https://doi.org/10.1007/s10593-020-02733-1},

number = {6},

pages = {800--804},

doi = {10.1007/s10593-020-02733-1}

}

MLA

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MLA Copy

Salimova, Elena V., et al. “Indole Derivatives of Fusidane Triterpenoids: Synthesis and the Antibacterial Activity.” Chemistry of Heterocyclic Compounds, vol. 56, no. 6, Jun. 2020, pp. 800-804. https://doi.org/10.1007/s10593-020-02733-1.