Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts
Nikolai O Vorozhtsov
1
,
Olga I. Yarovaya
2
,
Vitalii A Roznyatovskii
1
,
Boris N Tarasevich
1
,
Yuliya A Kozlovskaya
1
,
Aneliya I Petkova
1
,
Aleksander V Slita
3
,
Ekaterina O Sinegubova
3
,
Vladimir V. Zarubaev
3
,
Nariman F. Salakhutdinov
2
,
Publication type: Journal Article
Publication date: 2021-04-01
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
For the first time, convenient methods for the preparation of pyrazoline N-alkylidene salts based on terpene (camphor, camphorquinone, carvone) ketones, cage (adamantanone and norcamphor) ketones, and natural aldehydes (carvone and myrtenal) allowing the isolation of stable pyrazolinium salts in individual form were proposed. Optimization of the conditions for the synthesis of the target products was carried out. The antiviral activity of the synthesized salts was studied; among the tested compounds 1-bornylidene-3-phenylpyrazolinium tetrafluoroborate (IC50 6.2 μM, SI 107) exhibited the greatest activity against influenza A/Puerto Rico/8/34 (H1N1) virus.
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7
Total citations:
7
Citations from 2024:
5
(71.43%)
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Vorozhtsov N. O. et al. Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts // Chemistry of Heterocyclic Compounds. 2021. Vol. 57. No. 4. pp. 432-441.
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Vorozhtsov N. O., Yarovaya O. I., Roznyatovskii V. A., Tarasevich B. N., Kozlovskaya Y. A., Petkova A. I., Slita A. V., Sinegubova E. O., Zarubaev V. V., Salakhutdinov N. F., Beloglazkina E. K. Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts // Chemistry of Heterocyclic Compounds. 2021. Vol. 57. No. 4. pp. 432-441.
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TY - JOUR
DO - 10.1007/s10593-021-02921-7
UR - https://link.springer.com/10.1007/s10593-021-02921-7
TI - Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts
T2 - Chemistry of Heterocyclic Compounds
AU - Vorozhtsov, Nikolai O
AU - Yarovaya, Olga I.
AU - Roznyatovskii, Vitalii A
AU - Tarasevich, Boris N
AU - Kozlovskaya, Yuliya A
AU - Petkova, Aneliya I
AU - Slita, Aleksander V
AU - Sinegubova, Ekaterina O
AU - Zarubaev, Vladimir V.
AU - Salakhutdinov, Nariman F.
AU - Beloglazkina, Elena K
PY - 2021
DA - 2021/04/01
PB - Springer Nature
SP - 432-441
IS - 4
VL - 57
SN - 0009-3122
SN - 1573-8353
ER -
Cite this
BibTex (up to 50 authors)
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@article{2021_Vorozhtsov,
author = {Nikolai O Vorozhtsov and Olga I. Yarovaya and Vitalii A Roznyatovskii and Boris N Tarasevich and Yuliya A Kozlovskaya and Aneliya I Petkova and Aleksander V Slita and Ekaterina O Sinegubova and Vladimir V. Zarubaev and Nariman F. Salakhutdinov and Elena K Beloglazkina},
title = {Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts},
journal = {Chemistry of Heterocyclic Compounds},
year = {2021},
volume = {57},
publisher = {Springer Nature},
month = {apr},
url = {https://link.springer.com/10.1007/s10593-021-02921-7},
number = {4},
pages = {432--441},
doi = {10.1007/s10593-021-02921-7}
}
Cite this
MLA
Copy
Vorozhtsov, Nikolai O., et al. “Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts.” Chemistry of Heterocyclic Compounds, vol. 57, no. 4, Apr. 2021, pp. 432-441. https://link.springer.com/10.1007/s10593-021-02921-7.
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