Chemistry of Heterocyclic Compounds, volume 57, issue 11, pages 1130-1136
Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal
Publication type: Journal Article
Publication date: 2021-11-01
Journal:
Chemistry of Heterocyclic Compounds
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ISSN: 00093122, 15738353
Organic Chemistry
Abstract
A method for the introduction of the N , N -dimethylformamidine protective group in a series of six-membered 2-aminohetarene N -oxides was developed. It was shown that 2-amino derivatives of N -oxides of various six-membered heterocycles (pyridines, pyrimidines, pyrazines, tetrazines) successfully enter the reaction. The stability of the N , N -dimethylformamidine protecting group in 2-aminohetarene N -oxides was found to depend on the type of reaction medium.
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Karalash S. А. et al. Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal // Chemistry of Heterocyclic Compounds. 2021. Vol. 57. No. 11. pp. 1130-1136.
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Karalash S. А., Bystrov D. M., Ananyev I. V., Fershtat L. L. Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal // Chemistry of Heterocyclic Compounds. 2021. Vol. 57. No. 11. pp. 1130-1136.
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TY - JOUR
DO - 10.1007/s10593-021-03031-0
UR - https://doi.org/10.1007%2Fs10593-021-03031-0
TI - Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal
T2 - Chemistry of Heterocyclic Compounds
AU - Karalash, Sergey А
AU - Bystrov, Dmitry M.
AU - Ananyev, Ivan V.
AU - Fershtat, Leonid L
PY - 2021
DA - 2021/11/01 00:00:00
PB - Springer Nature
SP - 1130-1136
IS - 11
VL - 57
SN - 0009-3122
SN - 1573-8353
ER -
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@article{2021_Karalash,
author = {Sergey А Karalash and Dmitry M. Bystrov and Ivan V. Ananyev and Leonid L Fershtat},
title = {Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal},
journal = {Chemistry of Heterocyclic Compounds},
year = {2021},
volume = {57},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1007%2Fs10593-021-03031-0},
number = {11},
pages = {1130--1136},
doi = {10.1007/s10593-021-03031-0}
}
Cite this
MLA
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Karalash, Sergey А., et al. “Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal.” Chemistry of Heterocyclic Compounds, vol. 57, no. 11, Nov. 2021, pp. 1130-1136. https://doi.org/10.1007%2Fs10593-021-03031-0.
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