Open Access
Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol
Tatyana Usacheva
1
,
George Gamov
1
,
Anna Bychkova
2
,
Yuriy Anufrikov
3
,
Anna Shasherina
3
,
Diana Alister
1
,
Natalya Kuranova
1
,
Valentin Sharnin
1
Publication type: Journal Article
Publication date: 2022-03-05
scimago Q2
wos Q2
SJR: 0.551
CiteScore: 7.7
Impact factor: 3.1
ISSN: 13886150, 15882926, 03684466, 15728943, 14182874
PubMed ID:
35283663
Physical and Theoretical Chemistry
Condensed Matter Physics
Abstract
The paper reports the spectrofluorimetric and calorimetric study of binding of two hydrophobic biologically active molecules with antioxidant ability, flavonoids quercetin, and curcumin, to human serum albumin (HSA) in water, aqueous DMSO (0.05 and 0.1 mol. fraction of DMSO), and aqueous ethanol (0.05 mol. fraction of EtOH). Both flavonoids induce the quenching of HSA fluorescence. The stability constants of associates, as well as the changes in enthalpy of the reaction between quercetin and protein, were evaluated. The influence of solvent composition and additions of hydroxypropyl-β-cyclodextrin as a solubilizer of hydrophobic molecules, on the association processes is discussed.
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Metrics
9
Total citations:
9
Citations from 2024:
6
(66%)
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MLA
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GOST
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Usacheva T. et al. Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol // Journal of Thermal Analysis and Calorimetry. 2022. Vol. 147. No. 9. pp. 5511-5518.
GOST all authors (up to 50)
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Usacheva T., Gamov G., Bychkova A., Anufrikov Y., Shasherina A., Alister D., Kuranova N., Sharnin V. Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol // Journal of Thermal Analysis and Calorimetry. 2022. Vol. 147. No. 9. pp. 5511-5518.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s10973-022-11216-8
UR - https://link.springer.com/10.1007/s10973-022-11216-8
TI - Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol
T2 - Journal of Thermal Analysis and Calorimetry
AU - Usacheva, Tatyana
AU - Gamov, George
AU - Bychkova, Anna
AU - Anufrikov, Yuriy
AU - Shasherina, Anna
AU - Alister, Diana
AU - Kuranova, Natalya
AU - Sharnin, Valentin
PY - 2022
DA - 2022/03/05
PB - Springer Nature
SP - 5511-5518
IS - 9
VL - 147
PMID - 35283663
SN - 1388-6150
SN - 1588-2926
SN - 0368-4466
SN - 1572-8943
SN - 1418-2874
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Usacheva,
author = {Tatyana Usacheva and George Gamov and Anna Bychkova and Yuriy Anufrikov and Anna Shasherina and Diana Alister and Natalya Kuranova and Valentin Sharnin},
title = {Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol},
journal = {Journal of Thermal Analysis and Calorimetry},
year = {2022},
volume = {147},
publisher = {Springer Nature},
month = {mar},
url = {https://link.springer.com/10.1007/s10973-022-11216-8},
number = {9},
pages = {5511--5518},
doi = {10.1007/s10973-022-11216-8}
}
Cite this
MLA
Copy
Usacheva, Tatyana, et al. “Binding of quercetin and curcumin to human serum albumin in aqueous dimethyl sulfoxide and in aqueous ethanol.” Journal of Thermal Analysis and Calorimetry, vol. 147, no. 9, Mar. 2022, pp. 5511-5518. https://link.springer.com/10.1007/s10973-022-11216-8.