Pharmaceutical Chemistry Journal

, volume 55 , issue 11 , pages 1133-1137

Bioavailability and Safety of Dihydroquercetin (Review)

S V Orlova ¹

V V Tatarinov ²

E. A. Nikitina ¹

A V Sheremeta ¹

V A Ivlev ¹

V G Vasilev ¹

K V Paliy ¹

S V Goryainov ¹

Hide authors affiliations Show authors affiliations: 2 affiliations

Peoples’ Friendship University of Russia (RUDN), Moscow, Russia |

A. P. Vinogradov Institute of Geochemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk, Russia |

Publication type: Journal Article

Publication date: 2022-02-11

Springer Nature

Pharmaceutical Chemistry Journal

scimago Q4

wos Q4

SJR: 0.219

CiteScore: 1.4

Impact factor: 1.0

ISSN: 0091150X, 15739031

DOI: 10.1007/s11094-022-02548-8

Copy DOI

PubMed ID: 35194263

Drug Discovery

Pharmacology

Abstract

Dihydroquercetin (DHQ) is a bioflavonoid with high antioxidant, capillary-protective, and anti-inflammatory activity. DHQ has previously been used for treating Middle East respiratory syndrome coronavirus (MERS-CoV) infection and is currently considered a potential regulator of oxidative stress as part of COVID-19 multipurpose therapy. DHQ has a high safety profile but low bioavailability that limits its use. Innovative techniques (liposomization, crystal engineering, etc.) can be used to increase its bioavailability.

Found

2 citations

Terehov Roman

PhD in Pharmacy

29 publications, 628 citations

h-index: 10

Sechenov First Moscow State Medical University

Research interests

Natural polyphenols

Pharmaceutical Chemistry

Polymorphism

2 citations

Selivanova Irina

DSc in Pharmacy, professor

43 publications, 793 citations

h-index: 12

Sechenov First Moscow State Medical University

1 citation

Shipelin Vladimir

PhD in Health sciences

66 publications, 278 citations, 15 reviews

h-index: 9

Federal Research Center of Nutrition, Biotechnology and Food Safety

1 citation

Pankov Denis

🤝

8 publications, 52 citations

h-index: 5

Sechenov First Moscow State Medical University

Research interests

Organic Chemistry

Pharmaceutical Chemistry

1 citation

Bugaeva Maria

32 publications, 72 citations

h-index: 5

Russian Medical Academy of Continuous Professional Education

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GOST |

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GOST Copy

Orlova S. V. et al. Bioavailability and Safety of Dihydroquercetin (Review) // Pharmaceutical Chemistry Journal. 2022. Vol. 55. No. 11. pp. 1133-1137.

GOST all authors (up to 50) Copy

Orlova S. V., Tatarinov V. V., Nikitina E. A., Sheremeta A. V., Ivlev V. A., Vasilev V. G., Paliy K. V., Goryainov S. V. Bioavailability and Safety of Dihydroquercetin (Review) // Pharmaceutical Chemistry Journal. 2022. Vol. 55. No. 11. pp. 1133-1137.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1007/s11094-022-02548-8

UR - https://doi.org/10.1007/s11094-022-02548-8

TI - Bioavailability and Safety of Dihydroquercetin (Review)

T2 - Pharmaceutical Chemistry Journal

AU - Orlova, S V

AU - Tatarinov, V V

AU - Nikitina, E. A.

AU - Sheremeta, A V

AU - Ivlev, V A

AU - Vasilev, V G

AU - Paliy, K V

AU - Goryainov, S V

PY - 2022

DA - 2022/02/11

PB - Springer Nature

SP - 1133-1137

IS - 11

VL - 55

PMID - 35194263

SN - 0091-150X

SN - 1573-9031

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2022_Orlova,

author = {S V Orlova and V V Tatarinov and E. A. Nikitina and A V Sheremeta and V A Ivlev and V G Vasilev and K V Paliy and S V Goryainov},

title = {Bioavailability and Safety of Dihydroquercetin (Review)},

journal = {Pharmaceutical Chemistry Journal},

year = {2022},

volume = {55},

publisher = {Springer Nature},

month = {feb},

url = {https://doi.org/10.1007/s11094-022-02548-8},

number = {11},

pages = {1133--1137},

doi = {10.1007/s11094-022-02548-8}

}

MLA

Cite this

MLA Copy

Orlova, S. V., et al. “Bioavailability and Safety of Dihydroquercetin (Review).” Pharmaceutical Chemistry Journal, vol. 55, no. 11, Feb. 2022, pp. 1133-1137. https://doi.org/10.1007/s11094-022-02548-8.

Publisher

Springer Nature

Journal

Pharmaceutical Chemistry Journal

scimago Q4

wos Q4

SJR

0.219

CiteScore

1.4

Impact factor

1.0

ISSN

0091150X (Print)

15739031 (Electronic)