An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
Тип публикации: Journal Article
Дата публикации: 2012-07-20
scimago Q1
wos Q1
БС1
SJR: 0.871
CiteScore: 6.8
Impact factor: 4.3
ISSN: 07248741, 1573904X
PubMed ID:
22814904
Organic Chemistry
Pharmacology
Pharmaceutical Science
Molecular Medicine
Pharmacology (medical)
Biotechnology
Краткое описание
Tubulin dynamics is a promising target for new chemotherapeutic agents. The colchicine binding site is one of the most important pockets for potential tubulin polymerization destabilizers. Colchicine binding site inhibitors (CBSI) exert their biological effects by inhibiting tubulin assembly and suppressing microtubule formation. A large number of molecules interacting with the colchicine binding site have been designed and synthesized with significant structural diversity. CBSIs have been modified as to chemical structure as well as pharmacokinetic properties, and tested in order to find a highly potent, low toxicity agent for treatment of cancers. CBSIs are believed to act by a common mechanism via binding to the colchicine site on tubulin. The present review is a synopsis of compounds that have been reported in the past decade that have provided an increase in our understanding of the actions of CBSIs.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Топ-30
Журналы
|
10
20
30
40
50
60
70
|
|
|
European Journal of Medicinal Chemistry
69 публикаций, 10.42%
|
|
|
Bioorganic Chemistry
34 публикации, 5.14%
|
|
|
Journal of Medicinal Chemistry
29 публикаций, 4.38%
|
|
|
Molecules
21 публикация, 3.17%
|
|
|
Scientific Reports
19 публикаций, 2.87%
|
|
|
Bioorganic and Medicinal Chemistry
17 публикаций, 2.57%
|
|
|
Bioorganic and Medicinal Chemistry Letters
17 публикаций, 2.57%
|
|
|
Pharmaceuticals
15 публикаций, 2.27%
|
|
|
International Journal of Molecular Sciences
13 публикаций, 1.96%
|
|
|
Journal of Enzyme Inhibition and Medicinal Chemistry
12 публикаций, 1.81%
|
|
|
RSC Advances
11 публикаций, 1.66%
|
|
|
Oncotarget
9 публикаций, 1.36%
|
|
|
Future Medicinal Chemistry
9 публикаций, 1.36%
|
|
|
RSC Medicinal Chemistry
9 публикаций, 1.36%
|
|
|
Chemical Biology and Drug Design
7 публикаций, 1.06%
|
|
|
Medicinal Chemistry Research
6 публикаций, 0.91%
|
|
|
Anti-Cancer Agents in Medicinal Chemistry
6 публикаций, 0.91%
|
|
|
Cancers
6 публикаций, 0.91%
|
|
|
Frontiers in Chemistry
6 публикаций, 0.91%
|
|
|
PLoS ONE
6 публикаций, 0.91%
|
|
|
MedChemComm
6 публикаций, 0.91%
|
|
|
Molecular Cancer Therapeutics
6 публикаций, 0.91%
|
|
|
Journal of Molecular Structure
5 публикаций, 0.76%
|
|
|
Biochemical and Biophysical Research Communications
5 публикаций, 0.76%
|
|
|
ChemistrySelect
5 публикаций, 0.76%
|
|
|
ChemMedChem
5 публикаций, 0.76%
|
|
|
Journal of Natural Products
5 публикаций, 0.76%
|
|
|
Medicinal Chemistry
4 публикации, 0.6%
|
|
|
Frontiers in Pharmacology
4 публикации, 0.6%
|
|
|
10
20
30
40
50
60
70
|
Издатели
|
50
100
150
200
250
|
|
|
Elsevier
216 публикаций, 32.63%
|
|
|
MDPI
68 публикаций, 10.27%
|
|
|
Springer Nature
66 публикаций, 9.97%
|
|
|
Wiley
54 публикации, 8.16%
|
|
|
American Chemical Society (ACS)
53 публикации, 8.01%
|
|
|
Taylor & Francis
37 публикаций, 5.59%
|
|
|
Royal Society of Chemistry (RSC)
33 публикации, 4.98%
|
|
|
Bentham Science Publishers Ltd.
21 публикация, 3.17%
|
|
|
Frontiers Media S.A.
13 публикаций, 1.96%
|
|
|
Impact Journals
9 публикаций, 1.36%
|
|
|
American Association for Cancer Research (AACR)
9 публикаций, 1.36%
|
|
|
Public Library of Science (PLoS)
7 публикаций, 1.06%
|
|
|
Cold Spring Harbor Laboratory
7 публикаций, 1.06%
|
|
|
American Society for Pharmacology and Experimental Therapeutics
4 публикации, 0.6%
|
|
|
Pleiades Publishing
4 публикации, 0.6%
|
|
|
SAGE
3 публикации, 0.45%
|
|
|
Oxford University Press
3 публикации, 0.45%
|
|
|
APO Society of Specialists in Heart Failure
3 публикации, 0.45%
|
|
|
Hindawi Limited
3 публикации, 0.45%
|
|
|
Spandidos Publications
2 публикации, 0.3%
|
|
|
Ovid Technologies (Wolters Kluwer Health)
2 публикации, 0.3%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
2 публикации, 0.3%
|
|
|
The Japan Institute of Heterocyclic Chemistry
2 публикации, 0.3%
|
|
|
Scientific Societies
2 публикации, 0.3%
|
|
|
Georg Thieme Verlag KG
2 публикации, 0.3%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
2 публикации, 0.3%
|
|
|
Research Square Platform LLC
2 публикации, 0.3%
|
|
|
International Union of Crystallography (IUCr)
1 публикация, 0.15%
|
|
|
Mary Ann Liebert
1 публикация, 0.15%
|
|
|
50
100
150
200
250
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
662
Всего цитирований:
662
Цитирований c 2025:
48
(7.25%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Lu Y. et al. An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site // Pharmaceutical Research. 2012. Vol. 29. No. 11. pp. 2943-2971.
ГОСТ со всеми авторами (до 50)
Скопировать
Lu Y., Chen* J., Xiao M., Li W., Miller D. D. An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site // Pharmaceutical Research. 2012. Vol. 29. No. 11. pp. 2943-2971.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1007/s11095-012-0828-z
UR - https://doi.org/10.1007/s11095-012-0828-z
TI - An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
T2 - Pharmaceutical Research
AU - Lu, Yan
AU - Chen*, Jianjun
AU - Xiao, Min
AU - Li, Wei
AU - Miller, Duane D
PY - 2012
DA - 2012/07/20
PB - Springer Nature
SP - 2943-2971
IS - 11
VL - 29
PMID - 22814904
SN - 0724-8741
SN - 1573-904X
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2012_Lu,
author = {Yan Lu and Jianjun Chen* and Min Xiao and Wei Li and Duane D Miller},
title = {An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site},
journal = {Pharmaceutical Research},
year = {2012},
volume = {29},
publisher = {Springer Nature},
month = {jul},
url = {https://doi.org/10.1007/s11095-012-0828-z},
number = {11},
pages = {2943--2971},
doi = {10.1007/s11095-012-0828-z}
}
Цитировать
MLA
Скопировать
Lu, Yan, et al. “An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site.” Pharmaceutical Research, vol. 29, no. 11, Jul. 2012, pp. 2943-2971. https://doi.org/10.1007/s11095-012-0828-z.