Springer Nature
Russian Chemical Bulletin
,  volume 64 ,  issue 7 ,  pages 1560-1563

Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs

Publication type: Journal Article
Publication date: 2015-07-01
Springer Nature
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
A series of 2-aryl-5-arylmethylidene-1,3-oxazol-5(4H)-ones and 2-aryl-5-arylmethylidene-N-methyl-3,5-dihydro-4H-imidazol-4-ones was synthesized as structural analogs of combret- astatin A-4 (a compound possessing antitumor activity). (5Z)-5-[(4-Methoxyphenyl)methyl-idene]-3-methyl-2-(4-methylphenyl)-3,5-dihydro-4H-imidazol-4-one was found to exhibit the highest cytotoxicity against cells of human A549 lung carcinoma line (EC50 = 6±0.8 μmol L−1).
Found 
Found 

Top-30

Journals

1
2
Russian Chemical Bulletin
Russian Chemical Bulletin, 2, 50%
Russian Chemical Bulletin
2 publications, 50%
Bioorganic Chemistry
Bioorganic Chemistry, 2, 50%
Bioorganic Chemistry
2 publications, 50%
1
2

Publishers

1
2
Springer Nature
Springer Nature, 2, 50%
Springer Nature
2 publications, 50%
Elsevier
Elsevier, 2, 50%
Elsevier
2 publications, 50%
1
2
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
4
Share
Cite this
GOST |
Cite this
GOST Copy
Barskaia E. S. et al. Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs // Russian Chemical Bulletin. 2015. Vol. 64. No. 7. pp. 1560-1563.
GOST all authors (up to 50) Copy
Barskaia E. S., Beloglazkina A. A., Wobith B., Zefirov N. A., Majouga A. G., Beloglazkina E. K., Zyk N. V., Kuznetsov S. A., Zefirova O. N. Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs // Russian Chemical Bulletin. 2015. Vol. 64. No. 7. pp. 1560-1563.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s11172-015-1041-0
UR - http://link.springer.com/10.1007/s11172-015-1041-0
TI - Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs
T2 - Russian Chemical Bulletin
AU - Barskaia, E S
AU - Beloglazkina, A A
AU - Wobith, B
AU - Zefirov, N A
AU - Majouga, A G
AU - Beloglazkina, E K
AU - Zyk, N. V.
AU - Kuznetsov, S. A.
AU - Zefirova, O N
PY - 2015
DA - 2015/07/01
PB - Springer Nature
SP - 1560-1563
IS - 7
VL - 64
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Barskaia,
author = {E S Barskaia and A A Beloglazkina and B Wobith and N A Zefirov and A G Majouga and E K Beloglazkina and N. V. Zyk and S. A. Kuznetsov and O N Zefirova},
title = {Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs},
journal = {Russian Chemical Bulletin},
year = {2015},
volume = {64},
publisher = {Springer Nature},
month = {jul},
url = {http://link.springer.com/10.1007/s11172-015-1041-0},
number = {7},
pages = {1560--1563},
doi = {10.1007/s11172-015-1041-0}
}
MLA
Cite this
MLA Copy
Barskaia, E. S., et al. “Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs.” Russian Chemical Bulletin, vol. 64, no. 7, Jul. 2015, pp. 1560-1563. http://link.springer.com/10.1007/s11172-015-1041-0.