Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties
E R Milaeva
1, 2
,
D B Shpakovsky
1
,
I A Maklakova
1
,
K A Rufanov
1
,
M E Neganova
2
,
E. F. Shevtsova
2
,
A.V. Churakov
3
,
V A Babkova
4
,
D A Babkov
4
,
V A Kosolapov
4
,
A.A. Spasov
4
Publication type: Journal Article
Publication date: 2018-11-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
New diphenylsulfimide derivatives containing substituents with the 2,6-di-tert-butylphenol moiety at the nitrogen atom were synthesized. Their molecular structures were established by X-ray diffraction. Antioxidant activity was experimentally evaluated by spectrophotometry based on hydrogen transfer to the stable radicals, namely, 2,2-diphenyl-1-picrylhydrazyl and the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation (ABTS·+), and using in vitro lipid peroxidation in rat brain and liver homogenates. The presence of phenol and diphenylsulfimide moieties in one molecule leads to a significant enhancement of antioxidant activity. The new compounds exhibit moderate inhibitory activity against enzymes involved in carbohydrate and lipid metabolism. The evaluation of antiglycation activity showed that the new sulfimides taken at a concentration of 100 μmol L–1 have activity comparable with that of aminoguanidine.
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Total citations:
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Citations from 2024:
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(30%)
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GOST
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Milaeva E. R. et al. Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties // Russian Chemical Bulletin. 2018. Vol. 67. No. 11. pp. 2025-2034.
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Milaeva E. R., Shpakovsky D. B., Maklakova I. A., Rufanov K. A., Neganova M. E., Shevtsova E. F., Churakov A., Babkova V. A., Babkov D. A., Kosolapov V. A., Spasov A. Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties // Russian Chemical Bulletin. 2018. Vol. 67. No. 11. pp. 2025-2034.
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RIS
Copy
TY - JOUR
DO - 10.1007/s11172-018-2324-z
UR - http://link.springer.com/10.1007/s11172-018-2324-z
TI - Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties
T2 - Russian Chemical Bulletin
AU - Milaeva, E R
AU - Shpakovsky, D B
AU - Maklakova, I A
AU - Rufanov, K A
AU - Neganova, M E
AU - Shevtsova, E. F.
AU - Churakov, A.V.
AU - Babkova, V A
AU - Babkov, D A
AU - Kosolapov, V A
AU - Spasov, A.A.
PY - 2018
DA - 2018/11/01
PB - Springer Nature
SP - 2025-2034
IS - 11
VL - 67
SN - 1066-5285
SN - 1573-9171
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Milaeva,
author = {E R Milaeva and D B Shpakovsky and I A Maklakova and K A Rufanov and M E Neganova and E. F. Shevtsova and A.V. Churakov and V A Babkova and D A Babkov and V A Kosolapov and A.A. Spasov},
title = {Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties},
journal = {Russian Chemical Bulletin},
year = {2018},
volume = {67},
publisher = {Springer Nature},
month = {nov},
url = {http://link.springer.com/10.1007/s11172-018-2324-z},
number = {11},
pages = {2025--2034},
doi = {10.1007/s11172-018-2324-z}
}
Cite this
MLA
Copy
Milaeva, E. R., et al. “Novel diphenylsulfimide antioxidants containing 2,6-di-tert-butylphenol moieties.” Russian Chemical Bulletin, vol. 67, no. 11, Nov. 2018, pp. 2025-2034. http://link.springer.com/10.1007/s11172-018-2324-z.