том 68 издание 4 страницы 855-861

Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids

Тип публикацииJournal Article
Дата публикации2019-04-01
scimago Q3
БС2
SJR0.305
CiteScore2.8
Impact factor
ISSN10665285, 15739171
General Chemistry
Краткое описание
Pentacyclic triterpene hydroxy acids were transformed into acetylene-containing derivatives: propargyl esters at the carboxy group and O-(hex-5-ynoyl) derivatives at the hydroxy group. The cytotoxicity of the synthesized compounds was examined against HepG2 and Huh7 hepatocarcinoma cells and PC3 prostate cancer cells. The primary analysis of the structure—activity relationships was performed; glycyrrhetic acid derivatives showed the maximum enhancement in the cytotoxic properties upon introduction of an alkyne moiety.
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Russian Chemical Bulletin
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ГОСТ |
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Yamansarov E. Yu. et al. Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids // Russian Chemical Bulletin. 2019. Vol. 68. No. 4. pp. 855-861.
ГОСТ со всеми авторами (до 50) Скопировать
Yamansarov E. Yu., Saltykova I. V., Kovalev S. V., Petrov R. A., Shkil D. O., Seleznev E. I., Beloglazkina E. K., Majouga A. G. Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids // Russian Chemical Bulletin. 2019. Vol. 68. No. 4. pp. 855-861.
RIS |
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TY - JOUR
DO - 10.1007/s11172-019-2496-1
UR - http://link.springer.com/10.1007/s11172-019-2496-1
TI - Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids
T2 - Russian Chemical Bulletin
AU - Yamansarov, E Yu
AU - Saltykova, I V
AU - Kovalev, S V
AU - Petrov, R A
AU - Shkil, D O
AU - Seleznev, E I
AU - Beloglazkina, E K
AU - Majouga, A G
PY - 2019
DA - 2019/04/01
PB - Springer Nature
SP - 855-861
IS - 4
VL - 68
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2019_Yamansarov,
author = {E Yu Yamansarov and I V Saltykova and S V Kovalev and R A Petrov and D O Shkil and E I Seleznev and E K Beloglazkina and A G Majouga},
title = {Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids},
journal = {Russian Chemical Bulletin},
year = {2019},
volume = {68},
publisher = {Springer Nature},
month = {apr},
url = {http://link.springer.com/10.1007/s11172-019-2496-1},
number = {4},
pages = {855--861},
doi = {10.1007/s11172-019-2496-1}
}
MLA
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Yamansarov, E. Yu., et al. “Synthesis and cytotoxicity of new alkyne derivatives of pentacyclic triterpenoids.” Russian Chemical Bulletin, vol. 68, no. 4, Apr. 2019, pp. 855-861. http://link.springer.com/10.1007/s11172-019-2496-1.