Russian Chemical Bulletin, volume 71, issue 3, pages 489-495
Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo
Fedorov S.N.
1
,
Kuzmich A S
1
,
Agafonova I.G.
1
,
Sabutskii Yu E
1
,
Guzii A G
1
,
Popov R. S.
1
,
Ogurtsov V A
2
,
Rakitin O A
2
,
Polonik S G
1
Publication type: Journal Article
Publication date: 2022-03-01
Journal:
Russian Chemical Bulletin
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 1.7
ISSN: 10665285, 15739171
General Chemistry
Abstract
Nucleophilic substitution of the chlorine atom in 4,5-dichloro-1,2-dithiol-3-one using 1-thio-β-d-glucopyranose and its 2,3,4,6-tetra-O-acetyl derivative in acetonitrile resulted in two new 5-thioglucoside conjugates of 4-chloro-1,2-dithiol-3-one. The obtained thioglucosides showed cancer-preventive properties in a model of mouse epidermal JB6Cl41 P+ cells in soft agar, while one of them manifested antitumor activity in in vivo experiments in CD1 mice on a model of solid Ehrlich carcinoma. Both compounds were shown to inhibit basic AP-1-dependent transcriptional activity in murine JB6 Cl41 luc-AP-1 cells.
Citations by journals
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1
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MolBank
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MolBank
1 publication, 33.33%
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Marine Drugs
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Marine Drugs
1 publication, 33.33%
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Carbohydrate Research
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Carbohydrate Research
1 publication, 33.33%
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1
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Citations by publishers
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1
2
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
2 publications, 66.67%
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Elsevier
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Elsevier
1 publication, 33.33%
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1
2
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- We do not take into account publications that without a DOI.
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Fedorov S. et al. Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 489-495.
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Fedorov S., Kuzmich A. S., Agafonova I., Sabutskii Yu. E., Guzii A. G., Popov R. S., Ogurtsov V. A., Rakitin O. A., Polonik S. G. Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 489-495.
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TY - JOUR
DO - 10.1007/s11172-022-3438-x
UR - https://doi.org/10.1007%2Fs11172-022-3438-x
TI - Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo
T2 - Russian Chemical Bulletin
AU - Fedorov, S.N.
AU - Agafonova, I.G.
AU - Sabutskii, Yu E
AU - Guzii, A G
AU - Popov, R. S.
AU - Rakitin, O A
AU - Polonik, S G
AU - Kuzmich, A S
AU - Ogurtsov, V A
PY - 2022
DA - 2022/03/01 00:00:00
PB - Springer Nature
SP - 489-495
IS - 3
VL - 71
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2022_Fedorov,
author = {S.N. Fedorov and I.G. Agafonova and Yu E Sabutskii and A G Guzii and R. S. Popov and O A Rakitin and S G Polonik and A S Kuzmich and V A Ogurtsov},
title = {Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo},
journal = {Russian Chemical Bulletin},
year = {2022},
volume = {71},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007%2Fs11172-022-3438-x},
number = {3},
pages = {489--495},
doi = {10.1007/s11172-022-3438-x}
}
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MLA
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Fedorov, S.N., et al. “Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo.” Russian Chemical Bulletin, vol. 71, no. 3, Mar. 2022, pp. 489-495. https://doi.org/10.1007%2Fs11172-022-3438-x.