Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol
1
Southwest Foundation for Research and Education P. O. Box 28147, 8848 West Commerce Street, San Antonio, Texas 78284 U.S.A.
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Publication type: Journal Article
Publication date: 1977-04-01
scimago Q2
wos Q3
SJR: 0.620
CiteScore: 4.3
Impact factor: 2.3
ISSN: 0039128X, 18785867
PubMed ID:
867445
Organic Chemistry
Biochemistry
Molecular Biology
Pharmacology
Clinical Biochemistry
Endocrinology
Abstract
The syntheses of 3-O-carboxymethyl ether derivatives of estrone, estradiol-17beta, and estriol and the preparation of their bovine serum albumin (BSA) conjugates are described. These conjugates were employed for the generation of specific antisera suitable for radioimmunoassay (RIA) of estrone, estradiol-17beta, and estriol. The previous concept that specific antisera for estrogens cannot be obtained by employing estrogens derivatized at the 3-position is unfounded.
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RAO P. N., Moore P. H. Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol // Steroids. 1977. Vol. 29. No. 4. pp. 461-469.
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RAO P. N., Moore P. H. Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol // Steroids. 1977. Vol. 29. No. 4. pp. 461-469.
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TY - JOUR
DO - 10.1016/0039-128x(77)90066-6
UR - https://doi.org/10.1016/0039-128x(77)90066-6
TI - Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol
T2 - Steroids
AU - RAO, P. NARASIMHA
AU - Moore, Perry H.
PY - 1977
DA - 1977/04/01
PB - Elsevier
SP - 461-469
IS - 4
VL - 29
PMID - 867445
SN - 0039-128X
SN - 1878-5867
ER -
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BibTex (up to 50 authors)
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@article{1977_RAO,
author = {P. NARASIMHA RAO and Perry H. Moore},
title = {Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol},
journal = {Steroids},
year = {1977},
volume = {29},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/0039-128x(77)90066-6},
number = {4},
pages = {461--469},
doi = {10.1016/0039-128x(77)90066-6}
}
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MLA
Copy
RAO, P. NARASIMHA, and Perry H. Moore. “Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol.” Steroids, vol. 29, no. 4, Apr. 1977, pp. 461-469. https://doi.org/10.1016/0039-128x(77)90066-6.