Antitumour and anti-AIDS triterpenes from Celastrus hindsii.
Publication type: Journal Article
Publication date: 1997-04-01
scimago Q1
wos Q1
SJR: 0.726
CiteScore: 6.9
Impact factor: 3.4
ISSN: 00319422, 18733700
PubMed ID:
9115698
Biochemistry
Molecular Biology
General Medicine
Plant Science
Horticulture
Abstract
Four new triterpene compounds, celasdin-A, celasdin-C, anti-AIDS celasdin-B and cytotoxic maytenfolone-A, were isolated from Celastrus hindsii. The structural determination of maytenfolone-A, celasdin-A, celasdin-B and celasdin-C, as well as the structure-activity relationships of these new compounds and derivatives, are discussed. Maytenfolone-A was further confirmed by X-ray studies. Biological evaluation showed that Maytenfolone-A demonstrated cytotoxicity against hepatoma (HEPA-2B, ED50 = 2.3 micrograms ml-1) and nasopharynx carcinoma (KB, ED50 = 3.8 micrograms ml-1). Celasdin-B was found to exhibit anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 0.8 microgram ml-1).
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GOST
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Kuo Y., Li Ming Yang Kuo Antitumour and anti-AIDS triterpenes from Celastrus hindsii. // Phytochemistry. 1997. Vol. 44. No. 7. pp. 1275-1281.
GOST all authors (up to 50)
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Kuo Y., Li Ming Yang Kuo Antitumour and anti-AIDS triterpenes from Celastrus hindsii. // Phytochemistry. 1997. Vol. 44. No. 7. pp. 1275-1281.
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RIS
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TY - JOUR
DO - 10.1016/S0031-9422(96)00719-4
UR - https://doi.org/10.1016/S0031-9422(96)00719-4
TI - Antitumour and anti-AIDS triterpenes from Celastrus hindsii.
T2 - Phytochemistry
AU - Kuo, Yao-Lung
AU - Li Ming Yang Kuo
PY - 1997
DA - 1997/04/01
PB - Elsevier
SP - 1275-1281
IS - 7
VL - 44
PMID - 9115698
SN - 0031-9422
SN - 1873-3700
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1997_Kuo,
author = {Yao-Lung Kuo and Li Ming Yang Kuo},
title = {Antitumour and anti-AIDS triterpenes from Celastrus hindsii.},
journal = {Phytochemistry},
year = {1997},
volume = {44},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/S0031-9422(96)00719-4},
number = {7},
pages = {1275--1281},
doi = {10.1016/S0031-9422(96)00719-4}
}
Cite this
MLA
Copy
Kuo, Yao-Haur, et al. “Antitumour and anti-AIDS triterpenes from Celastrus hindsii..” Phytochemistry, vol. 44, no. 7, Apr. 1997, pp. 1275-1281. https://doi.org/10.1016/S0031-9422(96)00719-4.