Phytochemistry, volume 37, issue 5, pages 1305-1310

Sulphones derived from methylthiopropenoic acid amides from Glycosmis angustifolia

Harald GREGER ¹

Otmar HOFER ²

Gabriela Zechner ¹

Franz Hadacek ¹

Gerald Wurz ²

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Comparative Phytochemistry Department, Institute of Botany, University of Vienna, Rennweg 14, A‐1030 Wien, Austria |

Institute of Organic Chemistry, University of Vienna, Währingerstraße 38, A-1090 Wien, Austria |

Publication type: Journal Article

Publication date: 1994-11-01

Elsevier

Journal: Phytochemistry

scimago Q1

wos Q2

SJR: 0.667

CiteScore: 6.4

Impact factor: 3.2

ISSN: 00319422, 18733700

DOI: 10.1016/S0031-9422(00)90403-5

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Biochemistry

Molecular Biology

General Medicine

Plant Science

Horticulture

Abstract

Seven new sulphones derived from methylthiopropenoic acid amides have been isolated as dominant components from the methanolic leaf extract of Glycosmis angustifolia collected in Sri Lanka. All derivatives contained substituted phenethylamine moieties with prenyloxy (dambullins) or geranyloxy groups (gerambullins) in the para -position. Additional oxidation of the geranyl side chain leads to a diol (gerambullindiol) and to ketones (methylgerambullone and methylisogerambullone). The major component, methyldambullin, exhibited moderate antifungal activity.

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Publisher

Elsevier

Journal

Phytochemistry

scimago Q1

wos Q2

SJR

0.667

CiteScore

6.4

Impact factor

3.2

ISSN

00319422 (Print)

18733700 (Electronic)

Sulphones derived from methylthiopropenoic acid amides from Glycosmis angustifolia

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