Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors
Kiev S Ly
1
,
Michael A. Letavic
1
,
John A. Keith
1
,
Jennifer A. Miller
1
,
Emily M Stocking
1
,
Ann J Barbier
1
,
Pascal Bonaventure
1
,
Brian Lord
1
,
Xiaohui Jiang
1
,
Jamin D. Boggs
1
,
Lisa Dvorak
1
,
Kirsten L. Miller
1
,
Diane Nepomuceno
1
,
Sandy J. Wilson
1
,
Nicholas I Carruthers
1
1
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
|
Publication type: Journal Article
Publication date: 2008-01-01
scimago Q2
wos Q2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
PubMed ID:
18060777
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
The synthesis and biological activity of a new series of piperazine and diazepane amides is described. The new compounds are high affinity histamine H3 ligands and serotonin reuptake inhibitors.
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Total citations:
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Citations from 2024:
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(13.05%)
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MLA
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GOST
Copy
Ly K. S. et al. Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 1. pp. 39-43.
GOST all authors (up to 50)
Copy
Ly K. S., Letavic M. A., Keith J. A., Miller J. A., Stocking E. M., Barbier A. J., Bonaventure P., Lord B., Jiang X., Boggs J. D., Dvorak L., Miller K. L., Nepomuceno D., Wilson S. J., Carruthers N. I. Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 1. pp. 39-43.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.bmcl.2007.11.016
UR - https://doi.org/10.1016/j.bmcl.2007.11.016
TI - Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors
T2 - Bioorganic and Medicinal Chemistry Letters
AU - Ly, Kiev S
AU - Letavic, Michael A.
AU - Keith, John A.
AU - Miller, Jennifer A.
AU - Stocking, Emily M
AU - Barbier, Ann J
AU - Bonaventure, Pascal
AU - Lord, Brian
AU - Jiang, Xiaohui
AU - Boggs, Jamin D.
AU - Dvorak, Lisa
AU - Miller, Kirsten L.
AU - Nepomuceno, Diane
AU - Wilson, Sandy J.
AU - Carruthers, Nicholas I
PY - 2008
DA - 2008/01/01
PB - Elsevier
SP - 39-43
IS - 1
VL - 18
PMID - 18060777
SN - 0960-894X
SN - 1464-3405
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2008_Ly,
author = {Kiev S Ly and Michael A. Letavic and John A. Keith and Jennifer A. Miller and Emily M Stocking and Ann J Barbier and Pascal Bonaventure and Brian Lord and Xiaohui Jiang and Jamin D. Boggs and Lisa Dvorak and Kirsten L. Miller and Diane Nepomuceno and Sandy J. Wilson and Nicholas I Carruthers},
title = {Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {2008},
volume = {18},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.bmcl.2007.11.016},
number = {1},
pages = {39--43},
doi = {10.1016/j.bmcl.2007.11.016}
}
Cite this
MLA
Copy
Ly, Kiev S., et al. “Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.” Bioorganic and Medicinal Chemistry Letters, vol. 18, no. 1, Jan. 2008, pp. 39-43. https://doi.org/10.1016/j.bmcl.2007.11.016.