volume 155 pages 116282

Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals

Simon M., Indermaur M., Schenk D., Hosseinitabatabaei S., Willie B.M., Zysset P.
Publication typeJournal Article
Publication date2022-02-01
scimago Q1
wos Q2
SJR1.250
CiteScore8.2
Impact factor3.6
ISSN87563282, 18732763
Histology
Physiology
Endocrinology, Diabetes and Metabolism
Abstract
Osteogenesis Imperfecta (OI) is an inherited form of bone fragility characterised by impaired synthesis of type I collagen, altered trabecular bone architecture and reduced bone mass. High resolution peripheral computed tomography (HR-pQCT) is a powerful method to investigate bone morphology at peripheral sites including the weight-bearing distal tibia. The resulting 3D reconstructions can be used as a basis of micro-finite element (FE) or homogenized finite element (hFE) models for bone strength estimation. The hFE scheme uses homogenized local bone volume fraction (BV/TV) and anisotropy information (fabric) to compute healthy bone strength within a reasonable computation time using fabric-elasticity relationships. However, it is unclear if these relationships quantified previously for healthy controls are valid for trabecular bone from OI patients. Thus, the aim of this study is to investigate fabric-elasticity relationships in OI trabecular bone compared to healthy controls.
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Simon M. et al. Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals // Bone. 2022. Vol. 155. p. 116282.
GOST all authors (up to 50) Copy
Simon M., Indermaur M., Schenk D., Hosseinitabatabaei S., Willie B. M., Zysset P. Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals // Bone. 2022. Vol. 155. p. 116282.
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Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.bone.2021.116282
UR - https://doi.org/10.1016/j.bone.2021.116282
TI - Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals
T2 - Bone
AU - Simon, M
AU - Indermaur, M
AU - Schenk, D
AU - Hosseinitabatabaei, S
AU - Willie, B M
AU - Zysset, P
PY - 2022
DA - 2022/02/01
PB - Elsevier
SP - 116282
VL - 155
PMID - 34896360
SN - 8756-3282
SN - 1873-2763
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Simon,
author = {M Simon and M Indermaur and D Schenk and S Hosseinitabatabaei and B M Willie and P Zysset},
title = {Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals},
journal = {Bone},
year = {2022},
volume = {155},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016/j.bone.2021.116282},
pages = {116282},
doi = {10.1016/j.bone.2021.116282}
}