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Untargeted metabolomic LC-HRMS combined with Chemometric reveal metabolites change from sorghum flakes affected by food processing

Publication typeJournal Article
Publication date2025-06-01
scimago Q1
SJR1.256
CiteScore8.5
Impact factor
ISSN26660164
Abstract
A non-targeted UHPLC-HRMS metabolomics approach combined with chemometric analysis was employed to assess the change in metabolite profiles of sorghum flakes based on food processing techniques. The result showed that fatty acids were the most abundant metabolites, followed by lipids, amino acids, alkaloids, amines, and polyphenols, representing key metabolic markers influenced by food processing in sorghum flakes. Specific metabolites, including 15S-Hydroxyeicosatrienoic acid (15S-HETrE), terminaline, vitamin E acetate, furan fatty acid F6, all-trans-retinal, and fingolimod, exhibited increased concentrations during oven processing compared to raw sorghum, likely due to their thermal stability. This study provides valuable insights into effect of food processing effect on metabolites profiles.
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Anggraeni A. S. et al. Untargeted metabolomic LC-HRMS combined with Chemometric reveal metabolites change from sorghum flakes affected by food processing // Case Studies in Chemical and Environmental Engineering. 2025. Vol. 11. p. 101034.
GOST all authors (up to 50) Copy
Anggraeni A. S., Alam L. P. M., Utami I. D., Nurfahmi L., Noviana I. M. P., Suratno S. Untargeted metabolomic LC-HRMS combined with Chemometric reveal metabolites change from sorghum flakes affected by food processing // Case Studies in Chemical and Environmental Engineering. 2025. Vol. 11. p. 101034.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.cscee.2024.101034
UR - https://linkinghub.elsevier.com/retrieve/pii/S2666016424004286
TI - Untargeted metabolomic LC-HRMS combined with Chemometric reveal metabolites change from sorghum flakes affected by food processing
T2 - Case Studies in Chemical and Environmental Engineering
AU - Anggraeni, Ayu Septi
AU - Alam, Lucky Prabowo Miftachul
AU - Utami, Indrawati Dian
AU - Nurfahmi, Laely
AU - Noviana, Ika Mulawati Purwanti
AU - Suratno, S
PY - 2025
DA - 2025/06/01
PB - Elsevier
SP - 101034
VL - 11
SN - 2666-0164
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Anggraeni,
author = {Ayu Septi Anggraeni and Lucky Prabowo Miftachul Alam and Indrawati Dian Utami and Laely Nurfahmi and Ika Mulawati Purwanti Noviana and S Suratno},
title = {Untargeted metabolomic LC-HRMS combined with Chemometric reveal metabolites change from sorghum flakes affected by food processing},
journal = {Case Studies in Chemical and Environmental Engineering},
year = {2025},
volume = {11},
publisher = {Elsevier},
month = {jun},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2666016424004286},
pages = {101034},
doi = {10.1016/j.cscee.2024.101034}
}