Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study
2
Central Water Management Laboratory, Hrvatske vode, Ulica grada Vukovara 220, 10 000 Zagreb, Croatia
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Тип публикации: Journal Article
Дата публикации: 2009-05-01
scimago Q1
wos Q1
БС1
SJR: 2.205
CiteScore: 16.0
Impact factor: 7.3
ISSN: 02697491, 18736424
PubMed ID:
19200629
General Medicine
Health, Toxicology and Mutagenesis
Pollution
Toxicology
Краткое описание
This report describes an investigation of genotoxic effects in medicinal leech (Hirudo verbana) exposed to water and sediment of Lake Njivice (Krk Island, Croatia) contaminated by aluminium compounds. The levels of primary DNA damage in leech haemocytes and loss of DNA integrity caused by acute and chronic exposure to contaminated water and sediment were investigated using the alkaline comet assay. Genotoxic effects induced by acute exposure to contaminants were evaluated on leech haemocytes and blood cells of fish and mouse treated ex vivo. The effects of chronic exposure were assessed on haemocytes sampled from an animal kept under laboratory conditions on contaminated water and sediment for 180 days. The results indicate the DNA damaging potential of aluminium compounds present in an excess amount in tested samples.
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ГОСТ
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Mihaljević Z. et al. Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study // Environmental Pollution. 2009. Vol. 157. No. 5. pp. 1565-1572.
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MIHALJEVIĆ Z., TERNJEJ I., Stanković I., KEROVEC M., Kopjar N. Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study // Environmental Pollution. 2009. Vol. 157. No. 5. pp. 1565-1572.
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TY - JOUR
DO - 10.1016/j.envpol.2009.01.002
UR - https://doi.org/10.1016/j.envpol.2009.01.002
TI - Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study
T2 - Environmental Pollution
AU - MIHALJEVIĆ, ZLATKO
AU - TERNJEJ, IVANČICA
AU - Stanković, Iva
AU - KEROVEC, MLADEN
AU - Kopjar, Nevenka
PY - 2009
DA - 2009/05/01
PB - Elsevier
SP - 1565-1572
IS - 5
VL - 157
PMID - 19200629
SN - 0269-7491
SN - 1873-6424
ER -
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@article{2009_Mihaljević,
author = {ZLATKO MIHALJEVIĆ and IVANČICA TERNJEJ and Iva Stanković and MLADEN KEROVEC and Nevenka Kopjar},
title = {Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study},
journal = {Environmental Pollution},
year = {2009},
volume = {157},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.envpol.2009.01.002},
number = {5},
pages = {1565--1572},
doi = {10.1016/j.envpol.2009.01.002}
}
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MLA
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Mihaljević, Zlatko, et al. “Application of the comet assay and detection of DNA damage in haemocytes of medicinal leech affected by aluminium pollution: A case study.” Environmental Pollution, vol. 157, no. 5, May. 2009, pp. 1565-1572. https://doi.org/10.1016/j.envpol.2009.01.002.