volume 69 issue 15 pages 1952-1967

The Aging Cardiovascular System

Publication typeJournal Article
Publication date2017-04-10
scimago Q1
wos Q1
SJR9.015
CiteScore35.1
Impact factor22.3
ISSN07351097, 15583597
Cardiology and Cardiovascular Medicine
Abstract
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems. Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. The growing elderly population worldwide highlights the need to understand how aging promotes CVD in order to develop new strategies to confront this challenge. This review provides examples of some major unresolved clinical problems encountered in daily cardiovascular practice as we care for elderly patients. Next, the authors summarize the current understanding of the mechanisms implicated in cardiovascular aging, and the potential for targeting novel pathways implicated in endothelial dysfunction, mitochondrial oxidative stress, chromatin remodeling, and genomic instability. Lastly, the authors consider critical aspects of vascular repair, including autologous transplantation of bone marrow-derived stem cells in elderly patients.
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GOST |
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GOST Copy
Paneni F. et al. The Aging Cardiovascular System // Journal of the American College of Cardiology. 2017. Vol. 69. No. 15. pp. 1952-1967.
GOST all authors (up to 50) Copy
Paneni F., Diaz-Cañestro C., Libby P., Lüscher T., Camici G. G. The Aging Cardiovascular System // Journal of the American College of Cardiology. 2017. Vol. 69. No. 15. pp. 1952-1967.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.jacc.2017.01.064
UR - https://doi.org/10.1016/j.jacc.2017.01.064
TI - The Aging Cardiovascular System
T2 - Journal of the American College of Cardiology
AU - Paneni, Francesco
AU - Diaz-Cañestro, Candela
AU - Libby, Peter
AU - Lüscher, TF
AU - Camici, Giovanni G
PY - 2017
DA - 2017/04/10
PB - Elsevier
SP - 1952-1967
IS - 15
VL - 69
PMID - 28408026
SN - 0735-1097
SN - 1558-3597
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2017_Paneni,
author = {Francesco Paneni and Candela Diaz-Cañestro and Peter Libby and TF Lüscher and Giovanni G Camici},
title = {The Aging Cardiovascular System},
journal = {Journal of the American College of Cardiology},
year = {2017},
volume = {69},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.jacc.2017.01.064},
number = {15},
pages = {1952--1967},
doi = {10.1016/j.jacc.2017.01.064}
}
MLA
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MLA Copy
Paneni, Francesco, et al. “The Aging Cardiovascular System.” Journal of the American College of Cardiology, vol. 69, no. 15, Apr. 2017, pp. 1952-1967. https://doi.org/10.1016/j.jacc.2017.01.064.