Unlocking the potential of drug-drug cocrystals – A comprehensive review
1
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Mumbai 400019, India
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Publication type: Journal Article
Publication date: 2022-08-01
scimago Q1
wos Q1
SJR: 2.470
CiteScore: 19.4
Impact factor: 11.5
ISSN: 01683659, 18734995
PubMed ID:
35691502
Pharmaceutical Science
Abstract
Intensive research subjected to the improvement of solubility and bioavailability of certain drugs has popularized the formation of cocrystals, wherein the desired drug is non-ionically bonded to a coformer by means of weak bonds. This paper addresses how crystal engineering of two compatible drug components can enhance the physicochemical and therapeutic properties of either or both of the drugs, resulting in drug-drug cocrystals, with pertinent examples. The paper also discusses the continuous screening processes which are replacing the traditional methods of crystallization due to numerous benefits to the producer as well as the products. Although faced with certain regulatory and scale-up constraints, cocrystals provide immense opportunities to the field of novel drug development.
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Metrics
48
Total citations:
48
Citations from 2024:
36
(75%)
Cite this
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RIS |
BibTex
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GOST
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Banerjee M. et al. Unlocking the potential of drug-drug cocrystals – A comprehensive review // Journal of Controlled Release. 2022. Vol. 348. pp. 456-469.
GOST all authors (up to 50)
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Banerjee M., Nimkar K., Naik S., Patravale V. Unlocking the potential of drug-drug cocrystals – A comprehensive review // Journal of Controlled Release. 2022. Vol. 348. pp. 456-469.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jconrel.2022.06.003
UR - https://doi.org/10.1016/j.jconrel.2022.06.003
TI - Unlocking the potential of drug-drug cocrystals – A comprehensive review
T2 - Journal of Controlled Release
AU - Banerjee, Madhulika
AU - Nimkar, Kartik
AU - Naik, Shivraj
AU - Patravale, Vandana
PY - 2022
DA - 2022/08/01
PB - Elsevier
SP - 456-469
VL - 348
PMID - 35691502
SN - 0168-3659
SN - 1873-4995
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Banerjee,
author = {Madhulika Banerjee and Kartik Nimkar and Shivraj Naik and Vandana Patravale},
title = {Unlocking the potential of drug-drug cocrystals – A comprehensive review},
journal = {Journal of Controlled Release},
year = {2022},
volume = {348},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.jconrel.2022.06.003},
pages = {456--469},
doi = {10.1016/j.jconrel.2022.06.003}
}