Identification of a new sildenafil analogue in a health supplement
1
Pharmaceutical Laboratory, Applied Sciences Group, Health Science Authority, 11 Outram Road, Singapore 169078, Singapore
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Тип публикации: Journal Article
Дата публикации: 2011-11-01
scimago Q2
wos Q2
БС1
SJR: 0.628
CiteScore: 6.4
Impact factor: 3.1
ISSN: 07317085, 1873264X
PubMed ID:
21726974
Drug Discovery
Spectroscopy
Pharmaceutical Science
Clinical Biochemistry
Analytical Chemistry
Краткое описание
A sildenafil analogue was detected and isolated from a health supplement claimed for human use. The structure of this new analogue was elucidated using LC-UV, LC-Orbitrap-MS, IR spectroscopy, 1D and 2D NMR. It was characterized as dithio-desmethylcarbodenafil containing 2 thiocarbonyl groups instead of 2 carbonyl groups, and 4-methyl substitution, on the piperazine ring, rather than 4-ethyl substitution, when compared to sildenafil.
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ГОСТ |
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MLA
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ГОСТ
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Ge X. et al. Identification of a new sildenafil analogue in a health supplement // Journal of Pharmaceutical and Biomedical Analysis. 2011. Vol. 56. No. 3. pp. 491-496.
ГОСТ со всеми авторами (до 50)
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Ge X., Li L., Koh H., Low M. Y. Identification of a new sildenafil analogue in a health supplement // Journal of Pharmaceutical and Biomedical Analysis. 2011. Vol. 56. No. 3. pp. 491-496.
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RIS
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TY - JOUR
DO - 10.1016/j.jpba.2011.06.004
UR - https://doi.org/10.1016/j.jpba.2011.06.004
TI - Identification of a new sildenafil analogue in a health supplement
T2 - Journal of Pharmaceutical and Biomedical Analysis
AU - Ge, Xiaowei
AU - Li, Lin
AU - Koh, Hwee-Ling
AU - Low, Min Yong
PY - 2011
DA - 2011/11/01
PB - Elsevier
SP - 491-496
IS - 3
VL - 56
PMID - 21726974
SN - 0731-7085
SN - 1873-264X
ER -
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BibTex (до 50 авторов)
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@article{2011_Ge,
author = {Xiaowei Ge and Lin Li and Hwee-Ling Koh and Min Yong Low},
title = {Identification of a new sildenafil analogue in a health supplement},
journal = {Journal of Pharmaceutical and Biomedical Analysis},
year = {2011},
volume = {56},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016/j.jpba.2011.06.004},
number = {3},
pages = {491--496},
doi = {10.1016/j.jpba.2011.06.004}
}
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MLA
Скопировать
Ge, Xiaowei, et al. “Identification of a new sildenafil analogue in a health supplement.” Journal of Pharmaceutical and Biomedical Analysis, vol. 56, no. 3, Nov. 2011, pp. 491-496. https://doi.org/10.1016/j.jpba.2011.06.004.