Journal of Photochemistry and Photobiology B: Biology, volume 259, pages 112997
Insight into the efficiency of microalgae’ lipidic extracts as photosensitizers for Antimicrobial Photodynamic Therapy against Staphylococcus aureus
Inês Mendonça
1
,
Daniela Silva
1
,
Tiago A Conde
2, 3
,
Tatiana Maurício
2, 3
,
Maria Helena Cardoso
4
,
Hugo Silveira Pereira
5
,
Maria Bartolomeu
6
,
Cátia Vieira
1
,
M.Rosário M Domingues
2
,
4
Allmicroalgae Natural Products S.A., R&D Department, Rua 25 de Abril 19, 2445-287 Pataias, Portugal
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Publication type: Journal Article
Publication date: 2024-10-01
scimago Q1
wos Q1
SJR: 0.847
CiteScore: 12.1
Impact factor: 3.9
ISSN: 10111344, 18732682
Abstract
Antibacterial resistance causes around 1.27 million deaths annually around the globe and has been recognized as a top 3 priority health threat. Antimicrobial photodynamic therapy (aPDT) is considered a promising alternative to conventional antibiotic treatments. Algal lipid extracts have shown antibacterial effects when used as photosensitizers (PSs) in aPDT. In this work we assessed the photodynamic efficiency of lipidic extracts of microalgae belonging to different phyla (Bacillariophyta, Chlorophyta, Cyanobacteria, Haptophyta, Ochrophyta and Rhodophyta). All the extracts (at 1 mg mL
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