Advances in photodynamic antimicrobial chemotherapy

Publication typeJournal Article
Publication date2021-12-01
scimago Q1
wos Q1
SJR2.651
CiteScore26.3
Impact factor13.1
ISSN13895567, 18732739
Catalysis
Organic Chemistry
Physical and Theoretical Chemistry
Abstract
• Photodynamic therapy of microbial infections. • Photosensitization and reactive oxygen species generation. • Visible and NIR light sources for photodynamic therapy. • Recent clinical progresses of PACT. Photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT) combine light and photosensitizers to treat cancers and microbial infections, respectively. In PACT, the excitation of a photosensitizer drug with appropriate light generates reactive oxygen species (ROS) that kill pathogens in the proximity of the drug. PACT has considerably advanced with new light sources, biocompatible photosensitizers, bioconjugate methods, and efficient ROS production. The PACT technology has evolved to compete with or replace antibiotics, reducing the burden of antibiotic resistance. This review updates recent advances in PACT, with special references to light sources, photosensitizers, and emerging applications to microbial infestations. We also discuss PACT applied to COVID-19 causing SARS-CoV-2 treatment and disinfecting food materials and water. Finally, we discuss the pathogen selectivity and efficiency of PACT.
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GOST Copy
Anas A. et al. Advances in photodynamic antimicrobial chemotherapy // Journal of Photochemistry and Photobiology C: Photochemistry Reviews. 2021. Vol. 49. p. 100452.
GOST all authors (up to 50) Copy
Anas A., Sobhanan J., Sulfiya K. M., Jasmin C., Sreelakshmi P. K., Biju V. Advances in photodynamic antimicrobial chemotherapy // Journal of Photochemistry and Photobiology C: Photochemistry Reviews. 2021. Vol. 49. p. 100452.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.jphotochemrev.2021.100452
UR - https://doi.org/10.1016/j.jphotochemrev.2021.100452
TI - Advances in photodynamic antimicrobial chemotherapy
T2 - Journal of Photochemistry and Photobiology C: Photochemistry Reviews
AU - Anas, Abdulaziz
AU - Sobhanan, Jeladhara
AU - Sulfiya, K M
AU - Jasmin, C
AU - Sreelakshmi, P K
AU - Biju, V.
PY - 2021
DA - 2021/12/01
PB - Elsevier
SP - 100452
VL - 49
SN - 1389-5567
SN - 1873-2739
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Anas,
author = {Abdulaziz Anas and Jeladhara Sobhanan and K M Sulfiya and C Jasmin and P K Sreelakshmi and V. Biju},
title = {Advances in photodynamic antimicrobial chemotherapy},
journal = {Journal of Photochemistry and Photobiology C: Photochemistry Reviews},
year = {2021},
volume = {49},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.jphotochemrev.2021.100452},
pages = {100452},
doi = {10.1016/j.jphotochemrev.2021.100452}
}