Mendeleev Communications, volume 30, issue 5, pages 604-606
Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines
Publication type: Journal Article
Publication date: 2020-09-01
Journal:
Mendeleev Communications
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 1.9
ISSN: 09599436, 1364551X
General Chemistry
Abstract
Novel 4-amino-5-cyano-2-sulfonylpyrimidines were prepared based on three-component cyclization between isothiouronium salts, benzaldehydes and malononitrile, followed by oxidation of the sulfide moiety with Oxone. The cytotoxic activity of the synthesized compounds, as well as the induction of apoptosis, inhibition of the cell cycle and proliferation tests were performed on selected cancer cell lines A431, A549, A375, HCT 116, MCF7, LNCap and SH-SY5Y.
Citations by journals
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1
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Synthetic Communications
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Synthetic Communications
1 publication, 50%
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Organic Letters
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Organic Letters
1 publication, 50%
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1
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Citations by publishers
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1
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Taylor & Francis
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Taylor & Francis
1 publication, 50%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
1 publication, 50%
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1
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GOST
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Khochenkov D. A. et al. Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 604-606.
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Khochenkov D. A., Khochenkova Y. A., Machkova Y. S., Gasanov R. E., Stepanova E. V., Bunev A. S. Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 604-606.
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RIS
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TY - JOUR
DO - 10.1016/j.mencom.2020.09.017
UR - https://doi.org/10.1016%2Fj.mencom.2020.09.017
TI - Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines
T2 - Mendeleev Communications
AU - Khochenkov, Dmitry A.
AU - Khochenkova, Yulia A
AU - Machkova, Yulia S
AU - Gasanov, Rovshan E
AU - Stepanova, Eugenia V
AU - Bunev, Alexander S.
PY - 2020
DA - 2020/09/01 00:00:00
PB - Elsevier
SP - 604-606
IS - 5
VL - 30
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2020_Khochenkov,
author = {Dmitry A. Khochenkov and Yulia A Khochenkova and Yulia S Machkova and Rovshan E Gasanov and Eugenia V Stepanova and Alexander S. Bunev},
title = {Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Elsevier},
month = {sep},
url = {https://doi.org/10.1016%2Fj.mencom.2020.09.017},
number = {5},
pages = {604--606},
doi = {10.1016/j.mencom.2020.09.017}
}
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MLA
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Khochenkov, Dmitry A., et al. “Synthesis and cytotoxic activity of novel 4-amino-5-cyano-2-sulfonylpyrimidines.” Mendeleev Communications, vol. 30, no. 5, Sep. 2020, pp. 604-606. https://doi.org/10.1016%2Fj.mencom.2020.09.017.