Adolescent PCOS: a postpubertal central obesity syndrome
1
Publication type: Journal Article
Publication date: 2023-05-01
scimago Q1
wos Q1
SJR: 3.577
CiteScore: 21.9
Impact factor: 13.8
ISSN: 14714914, 1471499X
PubMed ID:
36964058
Molecular Biology
Molecular Medicine
Abstract
Adolescent polycystic ovary syndrome (PCOS) is a highly prevalent, reversible, endocrine-metabolic mode essentially driven by ectopic fat, which, in turn, often results from a mismatch between early adipogenesis and later lipogenesis, or between prenatal and postnatal weight gain. The key features of adolescent PCOS are menstrual irregularity and androgen excess (hirsutism, acne, and/or high testosterone). Adolescent PCOS is frequently preceded by rapid maturation (early variants of adrenarche/pubarche and puberty/menarche, also accelerated by ectopic fat) and is diagnosed between 2 and 8 years after menarche, thus during late adolescence or early adulthood. Treatment of adolescent PCOS should not only focus on symptoms, but also reduce the amount of ectopic fat, thereby aiming for an overall state of preconception health.
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66
Total citations:
66
Citations from 2024:
57
(86.36%)
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GOST
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Ibáñez L., de Zegher F. Adolescent PCOS: a postpubertal central obesity syndrome // Trends in Molecular Medicine. 2023. Vol. 29. No. 5. pp. 354-363.
GOST all authors (up to 50)
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Ibáñez L., de Zegher F. Adolescent PCOS: a postpubertal central obesity syndrome // Trends in Molecular Medicine. 2023. Vol. 29. No. 5. pp. 354-363.
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TY - JOUR
DO - 10.1016/j.molmed.2023.02.006
UR - https://doi.org/10.1016/j.molmed.2023.02.006
TI - Adolescent PCOS: a postpubertal central obesity syndrome
T2 - Trends in Molecular Medicine
AU - Ibáñez, Lourdes
AU - de Zegher, Francis
PY - 2023
DA - 2023/05/01
PB - Elsevier
SP - 354-363
IS - 5
VL - 29
PMID - 36964058
SN - 1471-4914
SN - 1471-499X
ER -
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BibTex (up to 50 authors)
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@article{2023_Ibáñez,
author = {Lourdes Ibáñez and Francis de Zegher},
title = {Adolescent PCOS: a postpubertal central obesity syndrome},
journal = {Trends in Molecular Medicine},
year = {2023},
volume = {29},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.molmed.2023.02.006},
number = {5},
pages = {354--363},
doi = {10.1016/j.molmed.2023.02.006}
}
Cite this
MLA
Copy
Ibáñez, Lourdes, et al. “Adolescent PCOS: a postpubertal central obesity syndrome.” Trends in Molecular Medicine, vol. 29, no. 5, May. 2023, pp. 354-363. https://doi.org/10.1016/j.molmed.2023.02.006.