New 1,3,4-thiadiazoles based on thiophene-2-carboxylic acid: Synthesis, characterization, and antimicrobial activities
Publication type: Journal Article
Publication date: 2020-03-01
scimago Q2
wos Q2
SJR: 0.628
CiteScore: 8.0
Impact factor: 4.7
ISSN: 00222860, 18728014
Organic Chemistry
Inorganic Chemistry
Spectroscopy
Analytical Chemistry
Abstract
Novel 1,3,4-thiadiazole derivatives were prepared by cyclization reaction of thiophene-2-carboxylic acid with N-arylthiosemicarbazides and POCl3. The antibacterial activities of the synthesized compounds were tested against Gram-negative bacteria (Salmonella enteritidis, Salmonella typhimurium, Enterobacter aerogenes, Salmonella infantis, Salmonella kentucky, and Escherichia coli), Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, and Enterococcus durans), and the fungus Candida albicans using the disk diffusion method. Selected 1,3,4-thiadiazole derivatives exhibited effective antimicrobial activity against S. aureus, C. albicans, S. typhimurium, E. aerogenes, and S. kentucky. Therefore, 1,3,4-thiadiazole derivatives can be considered as bioactive agents for pharmacological and medicinal applications. The synthesized compounds were characterized by using IR, 1H NMR, and 13C NMR spectroscopies and elemental analysis.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
|
|
|
Journal of Biomolecular Structure and Dynamics
2 publications, 6.9%
|
|
|
Russian Chemical Bulletin
1 publication, 3.45%
|
|
|
Letters in Drug Design and Discovery
1 publication, 3.45%
|
|
|
Molecules
1 publication, 3.45%
|
|
|
Journal of the Iranian Chemical Society
1 publication, 3.45%
|
|
|
Applied Biological Chemistry
1 publication, 3.45%
|
|
|
Chemistry of Heterocyclic Compounds
1 publication, 3.45%
|
|
|
Journal of Molecular Liquids
1 publication, 3.45%
|
|
|
Computational Biology and Chemistry
1 publication, 3.45%
|
|
|
Arabian Journal of Chemistry
1 publication, 3.45%
|
|
|
Journal of Saudi Chemical Society
1 publication, 3.45%
|
|
|
Journal of Heterocyclic Chemistry
1 publication, 3.45%
|
|
|
Archiv der Pharmazie
1 publication, 3.45%
|
|
|
RSC Medicinal Chemistry
1 publication, 3.45%
|
|
|
Russian Journal of Bioorganic Chemistry
1 publication, 3.45%
|
|
|
Polycyclic Aromatic Compounds
1 publication, 3.45%
|
|
|
Asian Journal of Research in Chemistry
1 publication, 3.45%
|
|
|
Combinatorial Chemistry and High Throughput Screening
1 publication, 3.45%
|
|
|
Asian Journal of Chemistry
1 publication, 3.45%
|
|
|
European Journal of Chemistry
1 publication, 3.45%
|
|
|
Vietnam Journal of Chemistry
1 publication, 3.45%
|
|
|
Mini-Reviews in Medicinal Chemistry
1 publication, 3.45%
|
|
|
Sustainable & Green Materials
1 publication, 3.45%
|
|
|
Scientific Reports
1 publication, 3.45%
|
|
|
Journal of Molecular Structure
1 publication, 3.45%
|
|
|
Total Chemistry
1 publication, 3.45%
|
|
|
Tetrahedron Letters
1 publication, 3.45%
|
|
|
1
2
|
Publishers
|
1
2
3
4
5
6
|
|
|
Elsevier
6 publications, 20.69%
|
|
|
Springer Nature
5 publications, 17.24%
|
|
|
Taylor & Francis
4 publications, 13.79%
|
|
|
Bentham Science Publishers Ltd.
3 publications, 10.34%
|
|
|
Wiley
3 publications, 10.34%
|
|
|
MDPI
1 publication, 3.45%
|
|
|
King Saud University
1 publication, 3.45%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 3.45%
|
|
|
Pleiades Publishing
1 publication, 3.45%
|
|
|
A and V Publications
1 publication, 3.45%
|
|
|
Asian Journal of Chemistry
1 publication, 3.45%
|
|
|
European Journal of Chemistry
1 publication, 3.45%
|
|
|
1
2
3
4
5
6
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
29
Total citations:
29
Citations from 2025:
5
(17.24%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Muğlu H., Yakan H., Shouaib H. A. New 1,3,4-thiadiazoles based on thiophene-2-carboxylic acid: Synthesis, characterization, and antimicrobial activities // Journal of Molecular Structure. 2020. Vol. 1203. p. 127470.
GOST all authors (up to 50)
Copy
Muğlu H., Yakan H., Shouaib H. A. New 1,3,4-thiadiazoles based on thiophene-2-carboxylic acid: Synthesis, characterization, and antimicrobial activities // Journal of Molecular Structure. 2020. Vol. 1203. p. 127470.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.molstruc.2019.127470
UR - https://linkinghub.elsevier.com/retrieve/pii/S0022286019315790
TI - New 1,3,4-thiadiazoles based on thiophene-2-carboxylic acid: Synthesis, characterization, and antimicrobial activities
T2 - Journal of Molecular Structure
AU - Muğlu, Halit
AU - Yakan, Hasan
AU - Shouaib, Hanan Almabrok
PY - 2020
DA - 2020/03/01
PB - Elsevier
SP - 127470
VL - 1203
SN - 0022-2860
SN - 1872-8014
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Muğlu,
author = {Halit Muğlu and Hasan Yakan and Hanan Almabrok Shouaib},
title = {New 1,3,4-thiadiazoles based on thiophene-2-carboxylic acid: Synthesis, characterization, and antimicrobial activities},
journal = {Journal of Molecular Structure},
year = {2020},
volume = {1203},
publisher = {Elsevier},
month = {mar},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0022286019315790},
pages = {127470},
doi = {10.1016/j.molstruc.2019.127470}
}