Physiology and Behavior, volume 80, issue 5, pages 647-655
Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus
Publication type: Journal Article
Publication date: 2004-02-01
Journal:
Physiology and Behavior
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 2.9
ISSN: 00319384, 1873507X
Experimental and Cognitive Psychology
Behavioral Neuroscience
Abstract
Amyloid beta-peptide (Abeta) plays an important role in the pathophysiology of Alzheimer's disease. The relationship between amnesia induced by central administration of aggregated Abeta(25-35) and neurodegeneration in the hippocampus was investigated. One month after a single intracerebroventricular injection of Abeta(25-35) (15 nmol), male Wistar rats were tested in an eight-arm radial maze. A quantitative evaluation of cell number in hippocampal regions was carried out on H&E-stained brain sections of rats used in the behavioral study. Indices of free radical-mediated processes in the hippocampus were evaluated in additional groups of animals 1, 3, 5, and 30 days after surgery. Abeta(25-35) induced impairments of working and reference memory (RM) as well as neurodegeneration in the CA1 but not in the CA3 field of the hippocampus. A significant correlation between both reference and working memory (WM) impairments and the neuronal cell loss in the hippocampal CA1 region was demonstrated. A gradually developing oxidative stress was evident in the hippocampus of rats treated with Abeta(25-35) as indicated by the increase in 2-thiobarbituric acid (TBARS) reactive substances and superoxide generation. These data suggest the involvement of oxidative stress in Abeta(25-35)-induced neurodegeneration and a relation between memory impairment and neurodegeneration in the CA1 subfield of the hippocampus.
Citations by journals
Citations by publishers
|
10
20
30
40
50
60
|
|
|
Elsevier
|
Elsevier
58 publications, 51.79%
|
|
Springer Nature
|
Springer Nature
21 publications, 18.75%
|
|
Wiley
|
Wiley
8 publications, 7.14%
|
|
Pleiades Publishing
|
Pleiades Publishing
4 publications, 3.57%
|
|
Taylor & Francis
|
Taylor & Francis
4 publications, 3.57%
|
|
Hindawi Limited
|
Hindawi Limited
3 publications, 2.68%
|
|
Mary Ann Liebert
|
Mary Ann Liebert
2 publications, 1.79%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
2 publications, 1.79%
|
|
Frontiers Media S.A.
|
Frontiers Media S.A.
2 publications, 1.79%
|
|
Public Library of Science (PLoS)
|
Public Library of Science (PLoS)
2 publications, 1.79%
|
|
American Society for Pharmacology and Experimental Therapeutics
|
American Society for Pharmacology and Experimental Therapeutics
1 publication, 0.89%
|
|
IOS Press
|
IOS Press
1 publication, 0.89%
|
|
SAGE
|
SAGE
1 publication, 0.89%
|
|
Wolters Kluwer Health
|
Wolters Kluwer Health
1 publication, 0.89%
|
|
Spandidos Publications
|
Spandidos Publications
1 publication, 0.89%
|
|
10
20
30
40
50
60
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2005,2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023],"ids":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","","","","","","","","","","","",""],"datasets":[{"label":"Citations number","data":[4,7,4,6,9,12,7,5,13,8,7,6,5,5,0,3,3,5,3],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["3.57","6.25","3.57","5.36","8.04","10.71","6.25","4.46","11.61","7.14","6.25","5.36","4.46","4.46",0,"2.68","2.68","4.46","2.68"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Behavioural Brain Research","Neuroscience","Neuroscience Letters","Psychopharmacology","Metabolic Brain Disease","Neuroscience and Behavioral Physiology","European Journal of Pharmacology","Journal of Medicinal Food","Antioxidants","Frontiers in Pharmacology","Neuropsychopharmacology","PLoS ONE","Brain Research","Neurobiology of Disease","Neuropeptides","Chemico-Biological Interactions","Journal of Neuroscience Research","International Journal of Neuroscience","Journal of Pharmacology and Experimental Therapeutics","Journal of Alzheimer's Disease","Journal of Psychopharmacology","Neurochemical Research","BMC Neuroscience","Amino Acids","BMC Complementary and Alternative Medicine","Cell Death Discovery","Pharmacological Reports","Pharmacology and Therapeutics","Translational Psychiatry","Journal of Molecular Neuroscience"],"ids":[17416,9057,22531,13024,6838,1742,1631,20846,16381,9788,8173,24963,22770,12156,4433,15240,21633,7200,21000,15085,20340,10309,23688,7448,9368,10757,23582,22929,15662,4307],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/Zy5YST233rzRbZP24I24MzZm64hz20ZV9qQopmMn_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/s6JtNKPXrzklKtbQZ4HrtzuJT0P7eHPX9U8x0nss_medium.webp","\/storage\/images\/resized\/KqWdDIHwzps3KNMz2kSZBC4SgMnkL3bwEKJqtZ2u_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp"],"datasets":[{"label":"","data":[8,6,5,4,3,3,3,2,2,2,2,2,2,2,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[7.14,5.36,4.46,3.57,2.68,2.68,2.68,1.79,1.79,1.79,1.79,1.79,1.79,1.79,1.79,1.79,1.79,1.79,0.89,0.89,0.89,0.89,0.89,0.89,0.89,0.89,0.89,0.89,0.89,0.89],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Springer Nature","Wiley","Pleiades Publishing","Taylor & Francis","Hindawi Limited","Mary Ann Liebert","Multidisciplinary Digital Publishing Institute (MDPI)","Frontiers Media S.A.","Public Library of Science (PLoS)","American Society for Pharmacology and Experimental Therapeutics","IOS Press","SAGE","Wolters Kluwer Health","Spandidos Publications"],"ids":[17,8,11,101,18,6921,230,202,208,344,695,29,31,32,1097],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/Zy5YST233rzRbZP24I24MzZm64hz20ZV9qQopmMn_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/PRGhlgB4OKRltSNtT39eA6wlnOTGRap1QQ6FQHih_medium.webp","\/storage\/images\/resized\/s6JtNKPXrzklKtbQZ4HrtzuJT0P7eHPX9U8x0nss_medium.webp","\/storage\/images\/resized\/KqWdDIHwzps3KNMz2kSZBC4SgMnkL3bwEKJqtZ2u_medium.webp","\/storage\/images\/resized\/ruydfaB80LDjlkYqsfOeUAZohOIODyq7bQzis5O7_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/8zKfOwdd5XirYzTQfqwp7U8IEQc8ckIOjyYQSBkk_medium.webp"],"datasets":[{"label":"","data":[58,21,8,4,4,3,2,2,2,2,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[51.79,18.75,7.14,3.57,3.57,2.68,1.79,1.79,1.79,1.79,0.89,0.89,0.89,0.89,0.89],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Stepanichev M. et al. Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus // Physiology and Behavior. 2004. Vol. 80. No. 5. pp. 647-655.
GOST all authors (up to 50)
Copy
Stepanichev M., Zdobnova I. M., Zarubenko I. I., Moiseeva Y. V., Lazareva N. A., Onufriev M. V., Gulyaeva N. V. Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus // Physiology and Behavior. 2004. Vol. 80. No. 5. pp. 647-655.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.physbeh.2003.11.003
UR - https://doi.org/10.1016%2Fj.physbeh.2003.11.003
TI - Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus
T2 - Physiology and Behavior
AU - Stepanichev, Mikhail
AU - Zdobnova, Irina M.
AU - Zarubenko, Irina I.
AU - Moiseeva, Yulia V.
AU - Lazareva, Natalia A.
AU - Onufriev, Mikhail V.
AU - Gulyaeva, Natalia V.
PY - 2004
DA - 2004/02/01 00:00:00
PB - Elsevier
SP - 647-655
IS - 5
VL - 80
SN - 0031-9384
SN - 1873-507X
ER -
Cite this
BibTex
Copy
@article{2004_Stepanichev,
author = {Mikhail Stepanichev and Irina M. Zdobnova and Irina I. Zarubenko and Yulia V. Moiseeva and Natalia A. Lazareva and Mikhail V. Onufriev and Natalia V. Gulyaeva},
title = {Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus},
journal = {Physiology and Behavior},
year = {2004},
volume = {80},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016%2Fj.physbeh.2003.11.003},
number = {5},
pages = {647--655},
doi = {10.1016/j.physbeh.2003.11.003}
}
Cite this
MLA
Copy
Stepanichev, Mikhail, et al. “Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus.” Physiology and Behavior, vol. 80, no. 5, Feb. 2004, pp. 647-655. https://doi.org/10.1016%2Fj.physbeh.2003.11.003.
Profiles