Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder
Тип публикации: Journal Article
Дата публикации: 2021-01-01
scimago Q1
wos Q1
БС1
SJR: 1.606
CiteScore: 8.6
Impact factor: 3.9
ISSN: 01651781, 18727123
PubMed ID:
33199026
Psychiatry and Mental health
Biological Psychiatry
Краткое описание
Major depressive disorder (MDD) is a debilitating psychiatric disease. The dysregulated cytokines in depression are assumed due to the hyperactivation of the immune system. Here we aimed to evaluate the serum interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in MDD. This study recruited 87 MDD patients and 87 age and sex-matched healthy controls (HCs). The increased levels of serum IL-1β and TNF-α were observed among MDD patients. These higher levels of peripheral markers were positively correlated with the severity of depression. Therefore, the elevated levels of serum IL-1β and TNF-α might be used as risk assessment indicators for depression.
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ГОСТ
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Das R. et al. Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder // Psychiatry Research. 2021. Vol. 295. p. 113568.
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Das R., Emon M. P. Z., Shahriar M. H., Nahar Z., Islam S. M. N., Bhuiyan M. A., Islam N., Islam R. Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder // Psychiatry Research. 2021. Vol. 295. p. 113568.
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TY - JOUR
DO - 10.1016/j.psychres.2020.113568
UR - https://doi.org/10.1016/j.psychres.2020.113568
TI - Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder
T2 - Psychiatry Research
AU - Das, Rajesh
AU - Emon, Md Prova Zaman
AU - Shahriar, Mohammad Hasan
AU - Nahar, Zabun
AU - Islam, Sardar M. N.
AU - Bhuiyan, Mohiuddin Ahmed
AU - Islam, Nazrul
AU - Islam, Rabiul
PY - 2021
DA - 2021/01/01
PB - Elsevier
SP - 113568
VL - 295
PMID - 33199026
SN - 0165-1781
SN - 1872-7123
ER -
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BibTex (до 50 авторов)
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@article{2021_Das,
author = {Rajesh Das and Md Prova Zaman Emon and Mohammad Hasan Shahriar and Zabun Nahar and Sardar M. N. Islam and Mohiuddin Ahmed Bhuiyan and Nazrul Islam and Rabiul Islam},
title = {Higher levels of serum IL-1β and TNF-α are associated with an increased probability of major depressive disorder},
journal = {Psychiatry Research},
year = {2021},
volume = {295},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.psychres.2020.113568},
pages = {113568},
doi = {10.1016/j.psychres.2020.113568}
}