Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment
Publication type: Journal Article
Publication date: 2013-08-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Novel compounds bearing a joint thiazole and a Z-5-aminopent-3-enoic acid fragments have been synthesized from readily accessible 5-bromolevulinic esters through a sequence of nucleophilic substitution, bromination, Hantzsch-type heterocyclization and Gabriel-like deprotection reactions. A majority of these reactions proceed in ionic liquid media that enhances their efficiency and selectivity in comparison to the corresponding reactions in conventional organic solvents. The compounds have a significant pharmaceutical potential.
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Total citations:
9
Citations from 2024:
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(11.11%)
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Zavozin A. G. et al. Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment // Tetrahedron. 2013. Vol. 69. No. 34. pp. 6975-6980.
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Zavozin A. G., Ignat’ev N. V., Schulte M., Khrustalev V. N. Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment // Tetrahedron. 2013. Vol. 69. No. 34. pp. 6975-6980.
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RIS
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TY - JOUR
DO - 10.1016/j.tet.2013.06.060
UR - https://doi.org/10.1016/j.tet.2013.06.060
TI - Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment
T2 - Tetrahedron
AU - Zavozin, Alexander G
AU - Ignat’ev, Nikolai V.
AU - Schulte, Michael
AU - Khrustalev, Victor N.
PY - 2013
DA - 2013/08/01
PB - Elsevier
SP - 6975-6980
IS - 34
VL - 69
SN - 0040-4020
SN - 1464-5416
ER -
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BibTex (up to 50 authors)
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@article{2013_Zavozin,
author = {Alexander G Zavozin and Nikolai V. Ignat’ev and Michael Schulte and Victor N. Khrustalev},
title = {Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment},
journal = {Tetrahedron},
year = {2013},
volume = {69},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.tet.2013.06.060},
number = {34},
pages = {6975--6980},
doi = {10.1016/j.tet.2013.06.060}
}
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MLA
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Zavozin, Alexander G., et al. “Synthesis of thiazole derivatives bearing an incorporated Z-5-aminopent-3-enoic acid fragment.” Tetrahedron, vol. 69, no. 34, Aug. 2013, pp. 6975-6980. https://doi.org/10.1016/j.tet.2013.06.060.