Tetrahedron Letters, volume 59, issue 8, pages 708-711
Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives
Publication type: Journal Article
Publication date: 2018-02-01
Journal:
Tetrahedron Letters
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 1.8
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A simple approach towards the pyrido[1,2-a:3,4-b′]diindole system via the reaction of indigo with methylene active compounds was used for the syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin, and their derivatives. It was also demonstrated that the reaction with ketones led to indigo decomposition and the formation of isatin derivatives. The derivative of fascaplysin with a phenyl substituent at C-7 demonstrated 2–3 times greater inhibitory activity against selected cancer cell lines than fascaplysin.
Citations by journals
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6
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Marine Drugs
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Marine Drugs
6 publications, 40%
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Molecules
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Molecules
2 publications, 13.33%
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International Review of Neurobiology
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International Review of Neurobiology
1 publication, 6.67%
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Journal of Pharmaceutical and Biomedical Analysis
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Journal of Pharmaceutical and Biomedical Analysis
1 publication, 6.67%
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Journal of Organic Chemistry
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Journal of Organic Chemistry
1 publication, 6.67%
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Natural Product Reports
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Natural Product Reports
1 publication, 6.67%
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Journal of Materials Chemistry C
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Journal of Materials Chemistry C
1 publication, 6.67%
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Chemistry - A European Journal
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Chemistry - A European Journal
1 publication, 6.67%
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Israel Journal of Chemistry
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Israel Journal of Chemistry
1 publication, 6.67%
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6
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Citations by publishers
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
8 publications, 53.33%
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Elsevier
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Elsevier
2 publications, 13.33%
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Royal Society of Chemistry (RSC)
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Royal Society of Chemistry (RSC)
2 publications, 13.33%
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Wiley
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Wiley
2 publications, 13.33%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
1 publication, 6.67%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Zhidkov M. E. et al. Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives // Tetrahedron Letters. 2018. Vol. 59. No. 8. pp. 708-711.
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Zhidkov M. E., Kantemirov A. V., Koisevnikov A. V., Andin A. N., Kuzmich A. S. Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives // Tetrahedron Letters. 2018. Vol. 59. No. 8. pp. 708-711.
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TY - JOUR
DO - 10.1016/j.tetlet.2018.01.023
UR - https://doi.org/10.1016%2Fj.tetlet.2018.01.023
TI - Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives
T2 - Tetrahedron Letters
AU - Zhidkov, Maxim E
AU - Kantemirov, Alexey V
AU - Koisevnikov, Alexey V
AU - Andin, Alexander N
AU - Kuzmich, Alexandra S
PY - 2018
DA - 2018/02/01 00:00:00
PB - Elsevier
SP - 708-711
IS - 8
VL - 59
SN - 0040-4039
SN - 1873-3581
ER -
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@article{2018_Zhidkov,
author = {Maxim E Zhidkov and Alexey V Kantemirov and Alexey V Koisevnikov and Alexander N Andin and Alexandra S Kuzmich},
title = {Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives},
journal = {Tetrahedron Letters},
year = {2018},
volume = {59},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016%2Fj.tetlet.2018.01.023},
number = {8},
pages = {708--711},
doi = {10.1016/j.tetlet.2018.01.023}
}
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MLA
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Zhidkov, Maxim E., et al. “Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives.” Tetrahedron Letters, vol. 59, no. 8, Feb. 2018, pp. 708-711. https://doi.org/10.1016%2Fj.tetlet.2018.01.023.