Tetrahedron Letters, volume 22, issue 52, pages 5239-5242
A novel anthraquinone annelation. A new approach to aklavinones.
Zareen Ahmed
1
,
Michael P. Cava
1
Publication type: Journal Article
Publication date: 1981-01-01
Journal:
Tetrahedron Letters
scimago Q3
wos Q3
SJR: 0.323
CiteScore: 3.5
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
1-Hydroxyanthraquinone has been annelated to a tetracyclic ketoester containing the major structural features of 4-deoxyaklavinone. The cyclization of the A-ring involves the first case of an anionic alkylation of an anthraquinone at a position which is not ortho to a phenolic function.
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