volume 9 issue 2 pages 117-126

Diabetes, metabolic disease, and telomere length

Publication typeJournal Article
Publication date2021-02-01
scimago Q1
wos Q1
SJR12.190
CiteScore64.2
Impact factor41.8
ISSN22138587, 22138595
Endocrinology
Endocrinology, Diabetes and Metabolism
Internal Medicine
Abstract

Summary

Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer. Emerging studies have highlighted the role of genetic and environmental factors, and explored the effect of modulating telomere length. We provide an overview of studies to date on diabetes and telomere length, and compare different methods and assays for evaluating telomere length and telomerase activity. We highlight the limitations of current studies and areas that warrant further research to unravel the link between diabetes and telomere length. The value of adding telomere length to clinical risk factors to improve risk prediction of diabetes and related complications also merits further investigation.
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GOST |
Cite this
GOST Copy
Cheng F. et al. Diabetes, metabolic disease, and telomere length // The Lancet Diabetes and Endocrinology. 2021. Vol. 9. No. 2. pp. 117-126.
GOST all authors (up to 50) Copy
Cheng F., Carroll L., Kong A. P., Januszewski A., Wong K. K., Jenkins A. J., Ma R. C. Diabetes, metabolic disease, and telomere length // The Lancet Diabetes and Endocrinology. 2021. Vol. 9. No. 2. pp. 117-126.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/s2213-8587(20)30365-x
UR - https://doi.org/10.1016/s2213-8587(20)30365-x
TI - Diabetes, metabolic disease, and telomere length
T2 - The Lancet Diabetes and Endocrinology
AU - Cheng, Feifei
AU - Carroll, Luke
AU - Kong, A. P.S.
AU - Januszewski, Andrzej
AU - Wong, Kwun Kiu
AU - Jenkins, Alicia J.
AU - Ma, R. C.W.
PY - 2021
DA - 2021/02/01
PB - Elsevier
SP - 117-126
IS - 2
VL - 9
PMID - 33248477
SN - 2213-8587
SN - 2213-8595
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Cheng,
author = {Feifei Cheng and Luke Carroll and A. P.S. Kong and Andrzej Januszewski and Kwun Kiu Wong and Alicia J. Jenkins and R. C.W. Ma},
title = {Diabetes, metabolic disease, and telomere length},
journal = {The Lancet Diabetes and Endocrinology},
year = {2021},
volume = {9},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016/s2213-8587(20)30365-x},
number = {2},
pages = {117--126},
doi = {10.1016/s2213-8587(20)30365-x}
}
MLA
Cite this
MLA Copy
Cheng, Feifei, et al. “Diabetes, metabolic disease, and telomere length.” The Lancet Diabetes and Endocrinology, vol. 9, no. 2, Feb. 2021, pp. 117-126. https://doi.org/10.1016/s2213-8587(20)30365-x.