Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation.
Тип публикации: Journal Article
Дата публикации: 1992-02-01
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 1.687
CiteScore: 9.4
Impact factor: 5.6
ISSN: 00062952, 18732968
PubMed ID:
1540216
Biochemistry
Pharmacology
Краткое описание
N omega-Hydroxy-L-arginine was found to cause vasodilation in arginine-depleted rabbit aorta. It is, therefore, likely to be a biosynthetic intermediate in the conversion of arginine to nitric oxide in this tissue. N-Hydroxyalkylguanidine compounds, including N omega-hydroxy-L-arginine were oxidized with various oxidizing agents and examined for their ability to release nitric oxide. All oxidizing agents tested were capable of oxidizing the N-hydroxyguanidine function but only lead tetra-acetate (Pb(OAc)4) and potassium ferricyanide/hydrogen peroxide (K3FeCN6/H2O2) were capable of generating significant amounts of nitric oxide. Oxidation with K3FeCN6, lead oxide (PbO2) and silver carbonate (Ag2CO3) resulted instead in the release of nitrous oxide (N2O) presumably through the initial release of nitroxyl (HNO).
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Метрики
107
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107
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ГОСТ
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Fukuto J. M. et al. Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation. // Biochemical Pharmacology. 1992. Vol. 43. No. 3. pp. 607-613.
ГОСТ со всеми авторами (до 50)
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Fukuto J. M., Wallace G. C., Hszieh R., Chaudhuri G. Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation. // Biochemical Pharmacology. 1992. Vol. 43. No. 3. pp. 607-613.
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RIS
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TY - JOUR
DO - 10.1016/0006-2952(92)90584-6
UR - https://doi.org/10.1016/0006-2952(92)90584-6
TI - Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation.
T2 - Biochemical Pharmacology
AU - Fukuto, Jon M.
AU - Wallace, Guillermo C
AU - Hszieh, Raina
AU - Chaudhuri, Gautam
PY - 1992
DA - 1992/02/01
PB - Elsevier
SP - 607-613
IS - 3
VL - 43
PMID - 1540216
SN - 0006-2952
SN - 1873-2968
ER -
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BibTex (до 50 авторов)
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@article{1992_Fukuto,
author = {Jon M. Fukuto and Guillermo C Wallace and Raina Hszieh and Gautam Chaudhuri},
title = {Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation.},
journal = {Biochemical Pharmacology},
year = {1992},
volume = {43},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016/0006-2952(92)90584-6},
number = {3},
pages = {607--613},
doi = {10.1016/0006-2952(92)90584-6}
}
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MLA
Скопировать
Fukuto, Jon M., et al. “Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation..” Biochemical Pharmacology, vol. 43, no. 3, Feb. 1992, pp. 607-613. https://doi.org/10.1016/0006-2952(92)90584-6.
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