Clinica Chimica Acta, volume 34, issue 1, pages 47-54
Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry
Publication type: Journal Article
Publication date: 1971-08-01
Journal:
Clinica Chimica Acta
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5
ISSN: 00098981, 18733492
Biochemistry
General Medicine
Clinical Biochemistry
Biochemistry (medical)
Abstract
The urinary phenolic acids from two patients with tyrosinemia being treated with low tyrosine-phenylalanine diets and from four normal controls were analysed by paper chromatography and by gas chromatography-mass spectrometry. The quantity of p -hydroxyphenylacetic acid from one of these patients was in the same range as two of the control subjects, but small quantities of p -hydroxyphenyllactic acid and p -hydroxyphenylpyruvic acid were detected in the patients' urine by gas chromatography-mass spectrometry. An attempt to reintroduce this patient to a normal diet was unsuccessful, and it is suggested that identification of the continuing defect can only be obtained using the high sensitivity and specificity of gas chromatography-mass spectrometry.
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GOST
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Crawhall J. C. et al. Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry // Clinica Chimica Acta. 1971. Vol. 34. No. 1. pp. 47-54.
GOST all authors (up to 50)
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Crawhall J. C., Mamer O., Tjoa S., Claveau J. C. Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry // Clinica Chimica Acta. 1971. Vol. 34. No. 1. pp. 47-54.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/0009-8981(71)90064-7
UR - https://doi.org/10.1016/0009-8981(71)90064-7
TI - Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry
T2 - Clinica Chimica Acta
AU - Crawhall, J. C.
AU - Mamer, O.
AU - Tjoa, S
AU - Claveau, J C
PY - 1971
DA - 1971/08/01
PB - Elsevier
SP - 47-54
IS - 1
VL - 34
SN - 0009-8981
SN - 1873-3492
ER -
Cite this
BibTex
Copy
@article{1971_Crawhall,
author = {J. C. Crawhall and O. Mamer and S Tjoa and J C Claveau},
title = {Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry},
journal = {Clinica Chimica Acta},
year = {1971},
volume = {34},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/0009-8981(71)90064-7},
number = {1},
pages = {47--54},
doi = {10.1016/0009-8981(71)90064-7}
}
Cite this
MLA
Copy
Crawhall, J. C., et al. “Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry.” Clinica Chimica Acta, vol. 34, no. 1, Aug. 1971, pp. 47-54. https://doi.org/10.1016/0009-8981(71)90064-7.