Clinica Chimica Acta, volume 34, issue 1, pages 47-54

Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry

J. C. Crawhall ¹

O. Mamer ¹

S Tjoa ¹

J C Claveau ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Division of Clinical Biochemistry, Department of Medicine, Royal Victoria Hospital and McGill University Clinic, Montreal, and Department of Pediatrics, Hŏtel Dieu St. Vallier, Chicoutimi, QuébecCanada |

Publication type: Journal Article

Publication date: 1971-08-01

Elsevier

Journal: Clinica Chimica Acta

Quartile SCImago

Quartile WOS

Impact factor: 5

ISSN: 00098981, 18733492

DOI: 10.1016/0009-8981(71)90064-7

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Biochemistry

General Medicine

Clinical Biochemistry

Biochemistry (medical)

Abstract

The urinary phenolic acids from two patients with tyrosinemia being treated with low tyrosine-phenylalanine diets and from four normal controls were analysed by paper chromatography and by gas chromatography-mass spectrometry. The quantity of p -hydroxyphenylacetic acid from one of these patients was in the same range as two of the control subjects, but small quantities of p -hydroxyphenyllactic acid and p -hydroxyphenylpyruvic acid were detected in the patients' urine by gas chromatography-mass spectrometry. An attempt to reintroduce this patient to a normal diet was unsuccessful, and it is suggested that identification of the continuing defect can only be obtained using the high sensitivity and specificity of gas chromatography-mass spectrometry.

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GOST |

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GOST Copy

Crawhall J. C. et al. Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry // Clinica Chimica Acta. 1971. Vol. 34. No. 1. pp. 47-54.

GOST all authors (up to 50) Copy

Crawhall J. C., Mamer O., Tjoa S., Claveau J. C. Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry // Clinica Chimica Acta. 1971. Vol. 34. No. 1. pp. 47-54.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/0009-8981(71)90064-7

UR - https://doi.org/10.1016/0009-8981(71)90064-7

TI - Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry

T2 - Clinica Chimica Acta

AU - Crawhall, J. C.

AU - Mamer, O.

AU - Tjoa, S

AU - Claveau, J C

PY - 1971

DA - 1971/08/01 00:00:00

PB - Elsevier

SP - 47-54

IS - 1

VL - 34

SN - 0009-8981

SN - 1873-3492

ER -

BibTex |

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BibTex Copy

@article{1971_Crawhall,

author = {J. C. Crawhall and O. Mamer and S Tjoa and J C Claveau},

title = {Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry},

journal = {Clinica Chimica Acta},

year = {1971},

volume = {34},

publisher = {Elsevier},

month = {aug},

url = {https://doi.org/10.1016/0009-8981(71)90064-7},

number = {1},

pages = {47--54},

doi = {10.1016/0009-8981(71)90064-7}

}

MLA

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MLA Copy

Crawhall, J. C., et al. “Urinary phenolic acids in tyrosinemia. identification and quantitation by gas chromatographymass spectrometry.” Clinica Chimica Acta, vol. 34, no. 1, Aug. 1971, pp. 47-54. https://doi.org/10.1016/0009-8981(71)90064-7.

Found error?

Publisher

Elsevier

Journal

Clinica Chimica Acta

Quartile SCImago

Quartile WOS

Impact factor

ISSN

00098981 (Print)
18733492 (Electronic)