Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation
Тип публикации: Journal Article
Дата публикации: 1995-02-01
scimago Q2
wos Q2
БС2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Краткое описание
Three new phosphate derivatives of paclitaxel-2′-ethylcarbonate 4a, 4b, and 4c, have been synthesized and evaluated for in vivo antitumor activity. All were soluble in water and two derivatives 4a and 4b were found to exhibit in vivo antitumor activity, comparable to paclitaxel in the M109 murine tumor model.
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ГОСТ
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Ueda Y. et al. Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation // Bioorganic and Medicinal Chemistry Letters. 1995. Vol. 5. No. 3. pp. 247-252.
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Ueda Y., Matiskella J. D., Mikkilineni A. B., Farina V., Knipe J. O., ROSE W. C., Casazza A., Vyas D. M. Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation // Bioorganic and Medicinal Chemistry Letters. 1995. Vol. 5. No. 3. pp. 247-252.
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TY - JOUR
DO - 10.1016/0960-894X(95)00018-O
UR - https://doi.org/10.1016/0960-894X(95)00018-O
TI - Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation
T2 - Bioorganic and Medicinal Chemistry Letters
AU - Ueda, Yasutsugu
AU - Matiskella, John D.
AU - Mikkilineni, Amarendra B
AU - Farina, Vittorio
AU - Knipe, Jay O.
AU - ROSE, WILLIAM C.
AU - Casazza, A.P
AU - Vyas, Dolatrai M
PY - 1995
DA - 1995/02/01
PB - Elsevier
SP - 247-252
IS - 3
VL - 5
SN - 0960-894X
SN - 1464-3405
ER -
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BibTex (до 50 авторов)
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@article{1995_Ueda,
author = {Yasutsugu Ueda and John D. Matiskella and Amarendra B Mikkilineni and Vittorio Farina and Jay O. Knipe and WILLIAM C. ROSE and A.P Casazza and Dolatrai M Vyas},
title = {Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {1995},
volume = {5},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016/0960-894X(95)00018-O},
number = {3},
pages = {247--252},
doi = {10.1016/0960-894X(95)00018-O}
}
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MLA
Скопировать
Ueda, Yasutsugu, et al. “Novel, water-soluble phosphate derivatives of 2′-ethoxy carbonylpaclitaxel as potential prodrugs of paclitaxel: Synthesis and antitumor evaluation.” Bioorganic and Medicinal Chemistry Letters, vol. 5, no. 3, Feb. 1995, pp. 247-252. https://doi.org/10.1016/0960-894X(95)00018-O.