Study of the physicochemical and biological properties of the new promising Ti–20Nb–13Ta–5Zr alloy for biomedical applications
Konstantin V Sergiyenko
1
,
Elena O Nasakina
1
,
Vladimir G Leontyev
1
,
Dmitry D Titov
1
,
Alena M Tsareva
1
,
Sergey V. Kannykin
3
,
Kristina A Kritskaya
4
,
Denis P Laryushkin
5
,
Konstantin N. Belosludtsev
6, 7
,
Sergey S. Antipov
8
,
Valery A. Kozlov
9, 10
,
Alexey V Shikirin
11, 12
,
Ilya V. Baimler
12, 13
,
Alexander V Simakin
14
,
Sergey V. Gudkov
14
,
Olga Kuznetsova
1
,
М A Sevostyanov
1
,
A. V. Berezhnov
4
,
Alexander Kulikov
5
,
Mikhail A. Volkov
15
,
Maksim Rebezov
16
Publication type: Journal Article
Publication date: 2020-11-01
scimago Q1
wos Q2
SJR: 0.808
CiteScore: 8.5
Impact factor: 4.7
ISSN: 02540584, 18793312
Condensed Matter Physics
General Materials Science
Abstract
A technology for producing a new homogeneous Ti–20Nb–13Ta–5Zr alloy has been developed. It is shown that the alloy is single-phase with a β-Ti type crystal lattice. The alloy has the required mechanical properties (tensile strength of about 745 MPa). On the surface of plates and wire made of alloy, a relief of micro- and nanoscale is observed. In terms of the ability to generate reactive oxygen species and long-lived reactive protein species, the Ti–20Nb–13Ta–5Zr alloy is more preferable than nitinol. It was established that cell cultures growing on plates or wire made of Ti–20Nb–13Ta–5Zr alloy had a significant mitotic index (2%). The number of viable cells was at least 95–96% of the overall cell count. According to the results of implantation of the alloy in the form of plates or wire ring to animals, it can be concluded that the alloy is biocompatible. The morphology of the surface of the samples did not change after biological experiments. It can be assumed that the alloy Ti–20Nb–13Ta–5Zr is a material potentially suitable for medical applications.
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Total citations:
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Citations from 2024:
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Konushkin S. V. et al. Study of the physicochemical and biological properties of the new promising Ti–20Nb–13Ta–5Zr alloy for biomedical applications // Materials Chemistry and Physics. 2020. Vol. 255. p. 123557.
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Konushkin S. V., Sergiyenko K. V., Nasakina E. O., Leontyev V. G., Titov D. D., Tsareva A. M., Dormidontov N. A., Kirsankin A. A., Kannykin S. V., Kritskaya K. A., Laryushkin D. P., Belosludtsev K. N., Antipov S. S., Kozlov V. A., Shikirin A. V., Baimler I. V., Simakin A. V., Gudkov S. V., Kuznetsova O., Sevostyanov М. A., Berezhnov A. V., Kulikov A., Volkov M. A., Rebezov M. Study of the physicochemical and biological properties of the new promising Ti–20Nb–13Ta–5Zr alloy for biomedical applications // Materials Chemistry and Physics. 2020. Vol. 255. p. 123557.
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TY - JOUR
DO - 10.1016/j.matchemphys.2020.123557
UR - https://linkinghub.elsevier.com/retrieve/pii/S0254058420309196
TI - Study of the physicochemical and biological properties of the new promising Ti–20Nb–13Ta–5Zr alloy for biomedical applications
T2 - Materials Chemistry and Physics
AU - Konushkin, Sergey V
AU - Sergiyenko, Konstantin V
AU - Nasakina, Elena O
AU - Leontyev, Vladimir G
AU - Titov, Dmitry D
AU - Tsareva, Alena M
AU - Dormidontov, Nikolay A
AU - Kirsankin, Andrey A
AU - Kannykin, Sergey V.
AU - Kritskaya, Kristina A
AU - Laryushkin, Denis P
AU - Belosludtsev, Konstantin N.
AU - Antipov, Sergey S.
AU - Kozlov, Valery A.
AU - Shikirin, Alexey V
AU - Baimler, Ilya V.
AU - Simakin, Alexander V
AU - Gudkov, Sergey V.
AU - Kuznetsova, Olga
AU - Sevostyanov, М A
AU - Berezhnov, A. V.
AU - Kulikov, Alexander
AU - Volkov, Mikhail A.
AU - Rebezov, Maksim
PY - 2020
DA - 2020/11/01
PB - Elsevier
SP - 123557
VL - 255
SN - 0254-0584
SN - 1879-3312
ER -
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@article{2020_Konushkin,
author = {Sergey V Konushkin and Konstantin V Sergiyenko and Elena O Nasakina and Vladimir G Leontyev and Dmitry D Titov and Alena M Tsareva and Nikolay A Dormidontov and Andrey A Kirsankin and Sergey V. Kannykin and Kristina A Kritskaya and Denis P Laryushkin and Konstantin N. Belosludtsev and Sergey S. Antipov and Valery A. Kozlov and Alexey V Shikirin and Ilya V. Baimler and Alexander V Simakin and Sergey V. Gudkov and Olga Kuznetsova and М A Sevostyanov and A. V. Berezhnov and Alexander Kulikov and Mikhail A. Volkov and Maksim Rebezov},
title = {Study of the physicochemical and biological properties of the new promising Ti–20Nb–13Ta–5Zr alloy for biomedical applications},
journal = {Materials Chemistry and Physics},
year = {2020},
volume = {255},
publisher = {Elsevier},
month = {nov},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0254058420309196},
pages = {123557},
doi = {10.1016/j.matchemphys.2020.123557}
}