Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production
Тип публикации: Journal Article
Дата публикации: 1996-12-01
scimago Q3
wos Q2
БС2
SJR: 0.423
CiteScore: 4
Impact factor: 2.5
ISSN: 00086215, 1873426X
PubMed ID:
9008844
Organic Chemistry
Biochemistry
General Medicine
Analytical Chemistry
Краткое описание
We report essentially complete 1H NMR assignments for the capsular polysaccharides from Neisseria meningitidis serotypes A, C, W-135, and Y. These polysaccharides are components of current polysaccharide vaccines against meningococcal infection and of the polysaccharide-protein conjugate vaccines under development. From these NMR data the pattern of O-acetylation was determined. O-Acetylation of the W-135 polysaccharide is reported for the first time. We also show that, for the Types C and W-135 polysaccharides a migration of O-acetyl groups occurs during storage in solution, and demonstrate that high field 1H NMR represents a simple and sensitive method to define the O-acetylation pattern of individual batches of these polysaccharides.
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94
Всего цитирований:
94
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(4.25%)
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ГОСТ |
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MLA
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ГОСТ
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Lemercinier X., Jones C. F. Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production // Carbohydrate Research. 1996. Vol. 296. No. 1-4. pp. 83-96.
ГОСТ со всеми авторами (до 50)
Скопировать
Lemercinier X., Jones C. F. Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production // Carbohydrate Research. 1996. Vol. 296. No. 1-4. pp. 83-96.
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RIS
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TY - JOUR
DO - 10.1016/s0008-6215(96)00253-4
UR - https://doi.org/10.1016/s0008-6215(96)00253-4
TI - Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production
T2 - Carbohydrate Research
AU - Lemercinier, Xavier
AU - Jones, Christopher F.
PY - 1996
DA - 1996/12/01
PB - Elsevier
SP - 83-96
IS - 1-4
VL - 296
PMID - 9008844
SN - 0008-6215
SN - 1873-426X
ER -
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BibTex (до 50 авторов)
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@article{1996_Lemercinier,
author = {Xavier Lemercinier and Christopher F. Jones},
title = {Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production},
journal = {Carbohydrate Research},
year = {1996},
volume = {296},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/s0008-6215(96)00253-4},
number = {1-4},
pages = {83--96},
doi = {10.1016/s0008-6215(96)00253-4}
}
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MLA
Скопировать
Lemercinier, Xavier, and Christopher F. Jones. “Full 1H NMR assignment and detailed O-acetylation patterns of capsular polysaccharides from Neisseria meningitidis used in vaccine production.” Carbohydrate Research, vol. 296, no. 1-4, Dec. 1996, pp. 83-96. https://doi.org/10.1016/s0008-6215(96)00253-4.