Basic local alignment search tool
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2
Publication type: Journal Article
Publication date: 1990-10-01
scimago Q1
wos Q2
SJR: 2.215
CiteScore: 10.1
Impact factor: 4.5
ISSN: 00222836, 10898638
PubMed ID:
2231712
Molecular Biology
Structural Biology
Abstract
A new approach to rapid sequence comparison, basic local alignment search tool (BLAST), directly approximates alignments that optimize a measure of local similarity, the maximal segment pair (MSP) score. Recent mathematical results on the stochastic properties of MSP scores allow an analysis of the performance of this method as well as the statistical significance of alignments it generates. The basic algorithm is simple and robust; it can be implemented in a number of ways and applied in a variety of contexts including straightforward DNA and protein sequence database searches, motif searches, gene identification searches, and in the analysis of multiple regions of similarity in long DNA sequences. In addition to its flexibility and tractability to mathematical analysis, BLAST is an order of magnitude faster than existing sequence comparison tools of comparable sensitivity.
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Total citations:
68704
Citations from 2024:
7622
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Cite this
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MLA
Cite this
GOST
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Altschul S. F. et al. Basic local alignment search tool // Journal of Molecular Biology. 1990. Vol. 215. No. 3. pp. 403-410.
GOST all authors (up to 50)
Copy
Altschul S. F., GISH W., MILLER W., Myers E. W., Lipman D. J. Basic local alignment search tool // Journal of Molecular Biology. 1990. Vol. 215. No. 3. pp. 403-410.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/S0022-2836(05)80360-2
UR - https://doi.org/10.1016/S0022-2836(05)80360-2
TI - Basic local alignment search tool
T2 - Journal of Molecular Biology
AU - Altschul, Stephen F.
AU - GISH, WARREN
AU - MILLER, WEBB
AU - Myers, Eugene W.
AU - Lipman, David J.
PY - 1990
DA - 1990/10/01
PB - Elsevier
SP - 403-410
IS - 3
VL - 215
PMID - 2231712
SN - 0022-2836
SN - 1089-8638
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1990_Altschul,
author = {Stephen F. Altschul and WARREN GISH and WEBB MILLER and Eugene W. Myers and David J. Lipman},
title = {Basic local alignment search tool},
journal = {Journal of Molecular Biology},
year = {1990},
volume = {215},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/S0022-2836(05)80360-2},
number = {3},
pages = {403--410},
doi = {10.1016/S0022-2836(05)80360-2}
}
Cite this
MLA
Copy
Altschul, Stephen F., et al. “Basic local alignment search tool.” Journal of Molecular Biology, vol. 215, no. 3, Oct. 1990, pp. 403-410. https://doi.org/10.1016/S0022-2836(05)80360-2.