volume 58 issue 34 pages 6795-6798

Novel bioactive isoquinoline alkaloids from Carduus crispus

Qing-Ying Zhang 1
Guangzhong Tu 2
Yuying Zhao 1
Tieming Cheng 1
Publication typeJournal Article
Publication date2002-08-01
scimago Q3
wos Q2
SJR0.426
CiteScore4.1
Impact factor2.2
ISSN00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Four novel isoquinoline alkaloids crispine B–E ( 2 – 5 ), along with a new natural isoquinoline alkaloid, crispine A ( 1 ), were isolated from Carduus crispus , and the structures were elucidated on the basis of spectroscopic data. Crispine A and B are alkaloids with pyrrolo-[2,1- a ]isoquinoline skeleton and crispine C–E are isoquinoline alkaloids with guanidinyl group. All compounds were evaluated for their cytotoxic activity ad compound 2 showed certain cytotoxic activity against some human-cancer lines in vitro. Four novel isoquinoline alkaloids crispine B–E ( 2 – 5 ), along with a new natural isoquinoline alkaloid, crispine A ( 1 ), were isolated from Carduus crispus , and the structures were elucidated on the basis of spectroscopic data. Compound 2 showed certain cytotoxic activity against some human-cancer lines in vitro.
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GOST |
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GOST Copy
Zhang Q. et al. Novel bioactive isoquinoline alkaloids from Carduus crispus // Tetrahedron. 2002. Vol. 58. No. 34. pp. 6795-6798.
GOST all authors (up to 50) Copy
Zhang Q., Tu G., Zhao Y., Cheng T. Novel bioactive isoquinoline alkaloids from Carduus crispus // Tetrahedron. 2002. Vol. 58. No. 34. pp. 6795-6798.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/S0040-4020(02)00792-5
UR - https://doi.org/10.1016/S0040-4020(02)00792-5
TI - Novel bioactive isoquinoline alkaloids from Carduus crispus
T2 - Tetrahedron
AU - Zhang, Qing-Ying
AU - Tu, Guangzhong
AU - Zhao, Yuying
AU - Cheng, Tieming
PY - 2002
DA - 2002/08/01
PB - Elsevier
SP - 6795-6798
IS - 34
VL - 58
SN - 0040-4020
SN - 1464-5416
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2002_Zhang,
author = {Qing-Ying Zhang and Guangzhong Tu and Yuying Zhao and Tieming Cheng},
title = {Novel bioactive isoquinoline alkaloids from Carduus crispus},
journal = {Tetrahedron},
year = {2002},
volume = {58},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/S0040-4020(02)00792-5},
number = {34},
pages = {6795--6798},
doi = {10.1016/S0040-4020(02)00792-5}
}
MLA
Cite this
MLA Copy
Zhang, Qing-Ying, et al. “Novel bioactive isoquinoline alkaloids from Carduus crispus.” Tetrahedron, vol. 58, no. 34, Aug. 2002, pp. 6795-6798. https://doi.org/10.1016/S0040-4020(02)00792-5.