Tetrahedron Letters, volume 44, issue 13, pages 2733-2736

A highly efficient olefin metathesis initiator: improved synthesis and reactivity studies

Aideen M Dunne 1
Stefan Mix 1
Siegfried Blechert 1
1
 
Institut für Chemie, Technische Universität Berlin, Strasse des 17, Juni 135, 10623 Berlin, Germany
Publication typeJournal Article
Publication date2003-03-25
scimago Q3
wos Q3
SJR0.323
CiteScore3.5
Impact factor1.5
ISSN00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The synthesis of ligand 8, required for the preparation of catalyst 4c has been optimised. Ligand exchange studies indicate that biphenyl-based alkylidene 4c initiates considerably faster than its unsubstituted analogue 4a. The performance of 4c in ring-opening cross metathesis reactions involving substrates containing unprotected chelating atoms is also reported.
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