Tetrahedron Letters, volume 44, issue 13, pages 2733-2736
A highly efficient olefin metathesis initiator: improved synthesis and reactivity studies
Aideen M Dunne
1
,
Stefan Mix
1
,
Siegfried Blechert
1
1
Institut für Chemie, Technische Universität Berlin, Strasse des 17, Juni 135, 10623 Berlin, Germany
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Publication type: Journal Article
Publication date: 2003-03-25
Journal:
Tetrahedron Letters
scimago Q3
wos Q3
SJR: 0.323
CiteScore: 3.5
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The synthesis of ligand 8, required for the preparation of catalyst 4c has been optimised. Ligand exchange studies indicate that biphenyl-based alkylidene 4c initiates considerably faster than its unsubstituted analogue 4a. The performance of 4c in ring-opening cross metathesis reactions involving substrates containing unprotected chelating atoms is also reported.
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